Isothermal thermal compression experiments with constant strain rate of Ti65 titanium alloy were carried out by using WDW-100H universal testing machine,the deformation temperatures is 840-1010 ℃ and strain rates is 0.001-0.1 s-1,and the strain-compen-sated Arrhenius constitutive equation and hot processing maps were established.The results show that the fluctuation of flow stress curve is large in 840-880 ℃,and the drop of stress from peak stress to stable stress is the minimum at 880 ℃,which is 24%,and it is more sensitive to temperature;the flow stress curve is more stable in 920-1010 ℃,and the drop of stress from peak stress to stable stress is the maximum at 920 ℃,which is 30%,and it is little sensitive to temperature.The strain-compensated Arrhenius constitutive equation can better predict the flow stress evolution laws of Ti65 titanium alloy under the deformation conditions of 840-1010 ℃ and 0.001-0.1 s-1.According to the correlation coefficient R=0.994 and the average relative error eAARE=6.9%,it is indicated that the model accuracy is high.The average strain rate sensitivity index m is 0.31.The hot processing map with strain of 1.0 was established,and it is found that Ti65 titanium alloy may be instability at low temperature and high strain rate,and the recrystallization behavior happens at low tempera-ture and low strain rate.Finally,the optimal hot deformation process parameters of Ti65 titanium alloy were obtained as:temperature range of 940-980 ℃ and strain rate range of 0.01-0.001 s-1.