The environmental factors that inhibit the anaerobic methanogenesis of waste-activated sludge were first described,including initial dissolved oxygen,organic load,temperature,and pH.The effects of endogenous inhibitors(e.g.,humic acid,ammonia,and salinity)on methane production of anaerobic di-gestion of waste-activated sludge were summarized.Humic acid can inhibit methanogenesis by competing with methanogens for electron donors and shifting the activity of the enzyme.Ammonia can affect methano-gens'activity.Salinity not only affects the methanogens'activity but also affects the release of intracellu-lar organic substances.The mechanisms of two commonly used obligate and non-obligate exogenous inhibi-tors on methane production are discussed.This review summarizes the recent advances in the inhibition of anaerobic methanogenesis of waste-activated sludge,which is expected to provide a theoretical reference for the resource utilization of sludge to produce acid.
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