Preparation and properties of magnetic mesoporous nanomaterials
Fe3O4 Nanospheres with good dispersibility were synthesized by hydrothermal method,and me-soporous silica(MSN)was coated on their outer layer.Chitosan(CS)and hyaluronic acid(HA)were further modified to form highly dispersed nanospheres Fe3O4@SiO2@MSN@CS@HA.The structure,morphology,particle size,and dispersibility of several nanospheres were characterized by scanning electron microscopy(SEM)and transmission electron microscopy(TEM).The outer layer content,specific sur-face area,and pore size were measured using a thermogravimetric analyzer(TGA)and a specific surface area analyzer(BET).The performance of the Fenton reaction was measured using a UV visible spectros-copy analyzer and its reaction rate was calculated.The results indicate that nanospheres have good disper-sibility and drug loading ability,and the divalent iron ions(Fe2+)they contain can further realize the po-tential of chemodynamic therapy(CDT)for tumors.
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