The molecular structure and application properties of four types of acrylamide polymers were summarized,such as anionic polymer,cationic polymer,zationic polymer of polymer and nonionic poly-mer,and put forward suggestions for the development of heat-resistant acid thickener.It is expected to provide a reference for the development and utilization of deep high temperature,low permeability and ex-tremely low permeability unconventional oil and gas fields.