首页|异噻唑啉酮及其衍生物的合成及生物活性综述

异噻唑啉酮及其衍生物的合成及生物活性综述

Review on synthesis and biological activity of isothiazolinone and its derivatives

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综述了有关异噻唑啉酮类化合物母核的合成方法、各个位点的修饰改造方法以及在工农医等领域的应用进展.该类化合物生物活性广泛,具有高效、低毒、广谱等优点,应用于杀菌、灭藻、防腐、防污等,是近年化工研究领域的热点,目前已有卡松(Kathon)和Sea-Nine 21 1(DCOIT)等商品化产品.异噻唑啉酮类化合物对工农业生产生活具有重要作用.重点讨论了近年来异噻唑啉酮及其衍生物在医药、农药、涂料、纺织、造纸、制革等领域的应用以及研究进展,最后对异噻唑啉酮类化合物的发展方向和应用前景做出展望.
The synthesis methods of isothiazolinone compounds,the modification methods of each site and the application progress in the fields of industry,agriculture and medicine are reviewed.The kind of com-pound has a wide range of biological activities,such as high efficiency,low toxicity and broad spectrum.It is mainly used in sterilization,algae killing,anticorrosion,antifouling and so on.It is a hot spot in the field of chemical research in recent years.At present,there are commercial products such as Kathon and Sea-Nine 211(DCOIT).Isothiazolinone compounds play an important role in industrial and agricultural pro-duction and life.The application and research progress of isothiazolinone and its derivatives in medicine,pesticide,coating,textile,papermaking,leather making and other fields in recent years were discussed.Fi-nally,the development direction and application prospect of isothiazolinone compounds were prospected.

isothiazolinonesynthesisderivativesbiological activity

李琦、杨一洲、闫合

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西北农林科技大学植物保护学院,陕西杨凌 712100

西北农林科技大学陕西省生物农药工程技术研究中心,陕西杨凌 712100

异噻唑啉酮 合成 衍生物 生物活性

国家自然科学基金面上项目

32072444

2024

应用化工
陕西省石油化工研究设计院 陕西省化工学会

应用化工

CSTPCD北大核心
影响因子:0.411
ISSN:1671-3206
年,卷(期):2024.53(7)