首页|异噻唑啉酮及其衍生物的合成及生物活性综述

异噻唑啉酮及其衍生物的合成及生物活性综述

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综述了有关异噻唑啉酮类化合物母核的合成方法、各个位点的修饰改造方法以及在工农医等领域的应用进展。该类化合物生物活性广泛,具有高效、低毒、广谱等优点,应用于杀菌、灭藻、防腐、防污等,是近年化工研究领域的热点,目前已有卡松(Kathon)和Sea-Nine 21 1(DCOIT)等商品化产品。异噻唑啉酮类化合物对工农业生产生活具有重要作用。重点讨论了近年来异噻唑啉酮及其衍生物在医药、农药、涂料、纺织、造纸、制革等领域的应用以及研究进展,最后对异噻唑啉酮类化合物的发展方向和应用前景做出展望。
Review on synthesis and biological activity of isothiazolinone and its derivatives
The synthesis methods of isothiazolinone compounds,the modification methods of each site and the application progress in the fields of industry,agriculture and medicine are reviewed.The kind of com-pound has a wide range of biological activities,such as high efficiency,low toxicity and broad spectrum.It is mainly used in sterilization,algae killing,anticorrosion,antifouling and so on.It is a hot spot in the field of chemical research in recent years.At present,there are commercial products such as Kathon and Sea-Nine 211(DCOIT).Isothiazolinone compounds play an important role in industrial and agricultural pro-duction and life.The application and research progress of isothiazolinone and its derivatives in medicine,pesticide,coating,textile,papermaking,leather making and other fields in recent years were discussed.Fi-nally,the development direction and application prospect of isothiazolinone compounds were prospected.

isothiazolinonesynthesisderivativesbiological activity

李琦、杨一洲、闫合

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西北农林科技大学植物保护学院,陕西杨凌 712100

西北农林科技大学陕西省生物农药工程技术研究中心,陕西杨凌 712100

异噻唑啉酮 合成 衍生物 生物活性

国家自然科学基金面上项目

32072444

2024

应用化工
陕西省石油化工研究设计院 陕西省化工学会

应用化工

CSTPCD北大核心
影响因子:0.411
ISSN:1671-3206
年,卷(期):2024.53(7)