三氯卡班对海水青鳉鱼生命发育初期的亚慢性毒性研究
Study on the subchronic toxicity of triclocarban to the early-life development of Oryzias Melastigma
孙哲诚 1梁川 1凌云哲 1陈杨 1马正茁 1刘志英 1徐炎华1
作者信息
- 1. 南京工业大学环境科学与工程学院,江苏南京 211816
- 折叠
摘要
研究了三氯卡班(TCC)对海水青鳉生命初期阶段的亚慢性毒性影响.结果表明,TCC会降低胚胎的心率和孵化率,并降低仔鱼的存活率.典型生物标志物测定发现,TCC会对胚胎的抗氧化系统和神经系统造成损伤.通过亚慢性毒性研究,可以进一步认识三氯卡班对海洋生物初期的潜在毒性影响和毒性机理,为TCC毒性的早期风险预警和控制提供了重要的理论指导.
Abstract
This study investigated the subchronic toxic effects of triclocarban(TCC)on the early life sta-ges of Oryzias Melastigma.The result showed that TCC could reduce the heart rate and hatching rate of embryos and decrease the survival rate of larvae.Typical biomarker assays revealed that TCC could cause damage to the antioxidant and nervous systems of embryos.Through subchronic toxicity studies,we can further understand the potential toxic effects and mechanisms of TCC on the early stages of marine organ-isms,providing essential theoretical guidance for the early risk assessment and control of TCC toxicity.
关键词
三氯卡班/海水青鳉/亚慢性毒性/生物标志物Key words
triclocarban/Oryzias Melastigma/subchronic toxicity/typical biomarker引用本文复制引用
基金项目
国家十三五重点研发课题(2017YFB0602500)
出版年
2024
NETL
NSTL
万方数据