首页|玻璃体切割手术+全视网膜光凝术治疗糖尿病视网膜病变的效果研究

玻璃体切割手术+全视网膜光凝术治疗糖尿病视网膜病变的效果研究

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目的:评估玻璃体切割手术(PPV)联合全视网膜光凝术(PRP)在治疗糖尿病视网膜病变(DR)中的疗效,分析对患者视觉功能的影响.方法:将收治的 54 例符合手术治疗适应证的 DR患者纳入研究,根据自愿原则分为对照组和治疗组.对照组 24 例行PPV治疗,治疗组 30 例接受PPV+PRP治疗.术前两组均注射康柏西普,比较分析两组治疗结果.结果:术后 1 周、术后 1 个月治疗组患者的最佳矫正视力值(BCVA)、眼内压(IOP)水平低于对照组,差异有统计学意义(P<0.05).术后 1 周、术后 1 个月治疗组患者周边视野 30°和 60°范围内的光敏度高于对照组,差异有统计学意义(P<0.05).术后 6 个月治疗组患者并发症发生率低于对照组,差异有统计学意义(P<0.05).结论:玻璃体切割手术联合全视网膜光凝术治疗糖尿病视网膜病变疗效较好,可有效控制病情发展,保护患者视力.
Study on the effect of pars plana vitrectomy and panretinal photocoagulation in the treatment of diabet-ic retinopathy
Objective:To evaluate the therapeutic effect of ranibizumab+pars plana vitrectomy(PPV)combined with panretinal photocoagulation(PRP)in the treatment of diabetic retinopathy(DR),and to analyze the effect on vis-ual function of patients.Methods:Fifty-four DR patients admitted to our hospital who met the indications for surgical treatment were included in the study,and the patients were divided into two groups according to the principle of volun-tariness.The control group(n=24)was treated with PPV,and the treatment group(n=30)received PPV+PRP treatment,and all patients in two groups were injected with anti-ranibizumab before surgery,and the treatment results were compared and analyzed.Results:The levels of best corrective visual acuity(BCVA)and intraocular pressure(IOP)in the treatment group at 1 week and 1 month after surgery were lower than those in the control group(P<0.05).The photosensitivity of patients with 30°and 60°peripheral field in the treatment group at 1 week and 1 month after surgery was higher than that in the control group(P<0.05).The incidence of complications at 6 months after surgery in the treatment group was lower than that in the control group(P<0.05).Conclusion:PPV+PRP is effective in the treat-ment of diabetic retinopathy,and the comprehensive application of these two surgical methods can effectively control the progrssion of the disease and can protect the patient's vision.

diabetesretinopathypanretinal photocoagulationpars plana vitrectomyrabizumab

王亮

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徐州医科大学附属沭阳医院,江苏 宿迁 223600

糖尿病 视网膜病变 全视网膜光凝术 玻璃体切割术 康柏西普

2025

临床医药实践
山西医科大学第二医院

临床医药实践

影响因子:0.735
ISSN:1671-8631
年,卷(期):2025.34(1)