Taking the mining process of the 3#coal seam in Sanyuan Coal Mine in Shanxi Province as an example,the idea of controlling ground subsidence through the zoning and isolation filling technology of overlying strata separation layer was proposed,the technical principles were analyzed and studied,and the key layers and separation layers were determined.Furthermore,an analysis was conducted on the implementation process of controlling ground settlement through injection pre-fracturing,pressure reduction,negative and low-pressure grouting,pressure increase,and holding pressure in the separation layer grouting of mining overlying strata.The results show that the separation and filling technology of overlying strata can improve the coal resource recovery rate,effectively solve the problem of coal pressure,control the collapse of overlying strata and ground subsidence deformation,ensure the safety of mining area structures and constructions,and achieve sustainable development of mining areas.