Physiology is an important fundamental course in medicine.Introduction of virtual simulation technology will be an important supplement and enhancement to traditional teaching modes in the course of physiology,because some teaching content can be visualized and human-machine interaction can be achieved.The physiology virtual simulation projects should be oriented towards teaching objec-tives and closely related to teaching content.In the design and implementation of virtual simulation projects,teachers should focus on developing scientific thinking in students,utilize advanced multimedia technology properly,and combine virtuality with reality to im-prove teaching effect.