Whooping cough,caused by Bordetella pertussis(Bp)infection,is an acute respiratory infectious disease in children transmitted through the air.Macrolide antibiotics have long been the first-line treatment for whooping cough.However,in recent years,macrolide-resistant Bordetella pertussis(MRBp)has been rarely reported outside China.The high prevalence of MRBp in China adds to the global challenge of whooping cough resurgence.The research firstly reports the emergence of clinical MRBp strains in China and has conducted extensive research in this field.This paper focuses on discussing the progress and challenges in the diagnosis,treatment and prevention of MRBp based on historical and recent studies.
关键词
百日咳/百日咳鲍特菌/耐大环内酯类百日咳鲍特菌/诊疗/防控
Key words
whooping cough/Bordetella pertussis/macrolide-resistant Bordetella pertussis/diagnosis and treatment/prevention and control