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不同性别大脑前动脉供血区梗死患者的临床特征比较

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目的 探讨不同性别大脑前动脉(ACA)供血区梗死的临床特征的差异。方法 采集患者一般临床资料、临床症状及神经功能障碍情况,影像学评估应用3。OT磁共振弥散成像和3D-TOF-MRA方法,明确梗死灶情况及责任血管。结果 37例ACA供血区梗死患者中男性占43%,女性占57%,不同性别患者的一般资料相比,男性组患者吸烟史、饮酒史比例高于女性(P<0。05);男性患者的血尿酸水平高于女性(t=2。22,P=0。033);男性患者出现肢体功能障碍的比例高于女性(100%与62%,x2=7。78,P=0。005),其中女性患者上肢肌力损害程度分级较男性患者轻(Z=2。21,P=0。034)。男性患者扣带回发生梗死灶的比例高于女性(63%与24%,x2=5。64,P=0。018),女性患者胼胝体膝部发生梗死灶的比例高于男性(48%与13%,x2=5。11,P=0。024),其他部位梗死灶无性别差异。结论 大脑前动脉供血区梗死女性患者多于男性,不同性别患者在梗死灶部位及肢体功能障碍方面有差异。
Comparison of clinical characteristics of anterior cerebral artery infarction in different genders
Objective To explore the differences in clinical characteristics of anterior cerebral artery(ACA)supply area infarction between different genders.Methods General clinical data,clinical symptoms,and neurological dysfunction of 37 patients were collected,and imaging evaluation was performed using 3.OT magnetic resonance diffusion imaging and 3D-TOF-MRA methods to clarify the infarct location and responsible blood vessels.Results Among the 37 patients with ACA blood supply area infarction,males accounted for 43%and females accounted for 57%.Compared with the general information of patients of different genders,the proportion of smoking and drinking history in the male group was higher than that in the female group(P<0.05).The blood uric acid level of male patients was higher than that of females(t=2.22,P=0.033).The proportion of male patients with limb dysfunction was higher than that of female patients(100%vs 62%,X2=7.78,P=0.005),among which the degree of upper limb muscle strength damage in female patients was milder than that in male patients(Z=2.21,P=0.034).The proportion of cingulate cortex infarcts in male patients was higher than that in female patients(63%vs 24%,x2=5.64,P=0.018),and the proportion of corpus callosum knee infarcts in female patients was higher than that in male patients(48%vs 13%,X2=5.11,P=0.024).There was no gender difference in other infarcts.Conclusion There are more female patients with anterior cerebral artery infarction than male patients,and there are differences in infarct sites and limb dysfunction between different genders.

Brain infarctionAnterior cerebral arteryGender factorsLimb dysfunction

王光胜、鲍俊杰、胡婷、田媛媛、黄利、顾汉沛、周金金

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223600 徐州医科大学附属沭阳医院神经内科

脑梗死 大脑前动脉 性别因素 肢体功能障碍

江苏省卫生健康委科研项目

Z2019032

2024

山西医药杂志
山西医药卫生传媒集团有限责任公司

山西医药杂志

影响因子:0.504
ISSN:0253-9926
年,卷(期):2024.53(5)
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