Therapeutic effect of nerve interventional thrombectomy on cerebral infarction and its influence on the prognosis of patients
Objective To observe the clinical effect of nerve interventional thrombectomy in the treatment of cerebral infarction and its influence on the prognosis of patients.Methods This article is a retrospective study.The subjects of the study were 160 patients with cerebral infarction admitted to Zhengzhou Central Hospital affiliated to Zhengzhou University from March 2021 to May 2022.According to different treatment methods,80 patients who received routine treatment were included in the control group,and the other 80 patients who received interventional embolectomy were included in the surgical group.The therapeutic effectiveness and safety of the two groups were compared.A logistic multiple regression model was used to analyze the impact of different treatment methods on the efficacy and prognosis of patients.Results After treatment,the National Health stroke scale(NIHSS)score in the surgical group was lower than that in the control group,and the vascular recanalization rate was higher[90％(72/80)]than that in the control group[79％(63/80)],while 6-Keto-prostaglandin F 1 alpha(6-kelo-PGF1α)was higher than that in the control group,and nitric oxide(NO)and endothelin(ET)were lower than those in the control group.The incidence of adverse events[5％(4/80)]was lower than that of the control group[(16％(13/80)](P＜0.05).Logistic multiple regression model analysis showed After treatment,NIHSS that was more than 10 points,blood vessels still blocked,intracranial hemorrhage,limb disorders,cognitive disorders and disease recurrence were lower than those in the control group(P＜0.05).Conclusion Neurointerventional embolectomy can promote the improvement of cerebral nervous function and vascular endothelial function in patients with cerebral infarction,and has positive significance in reducing the risk of adverse events and improving the prognosis of patients.
Brain infarctionAngiography,digital subtractionBrain nerve functionCerebral hemodynamicsVascular endothelial function
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