Effects of 25G vitrectomy for proliferative diabetes retinopathy on visual acuity,intraocular pressure level and inflammatory response indicators
Objective To investigate the effect of 25G vitrectomy on the visual acuity,intraocular pressure,and inflammatory response in patients with proliferative diabetes retinopathy(PDR).Methods A total of 82 PDR patients admitted to the hospital from June 2020 to May 2023 were selected as the study subjects.The 82 PDR patients were randomly divided into two groups using a random number table method.The control group(41 cases)received 23G vitrectomy treatment,while the observation group(41 cases)received 25G vitrectomy treatment.Compare and analyze the visual acuity,intraocular pressure levels,inflammatory reactions,and complications of the two groups of patients.Results The intraocular pressure level(13.1±2.6)mmHg,and complications(5％)of the observation group were lower than those of the control group(15.2±3.7)mmHg,and 27％,with statistical significance(P＜0.05).The total incidence of inflammatory reactions in the observation group was 10％(4/41),which was equivalent to 15％(6/41)in the control group,with no statistically significant difference(P＞0.05).The quality-of-life questionnaire(CLVQOL)for low vision patients in the observation group showed higher scores in distant vision,movement and light perception(79.9±4.6),daily living ability(83.2±5.8),reading and fine motor ability(82.1±5.5),and regulatory ability(84.1±5.0)compared to the control group(70.5±2.4),(72.9±3.7),(69.8±3.5),and(73.6±4.0),with statistically significant differences(P＜0.05).Conclusion The application of 25G vitrectomy in PDR patients has a significant effect.It can effectively improve the patients'intraocular pressure level and vision,improve their quality of life,and not increase inflammatory reactions,with fewer complications and high safety.
Diabetic retinopathyVitrectomyIntraocular pressureVisionInflammatory responseComplicationsQuality of life
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