Study on the influence of glucose and lipid metabolism on lactation in GDM patients and nutritional intervention strategies
Objective To analyze the impact of glucose and lipid metabolism on lactation in gestational diabetes mellitus(GDM)patients and explore specific nutritional intervention strategies.Methods A total of 112 GDM patients admitted to Xiuwu County People's Hospital from January 2021 to December 2022 were included in this retrospective study.According to postpartum lactation,52 patients with delayed postpartum lactation initiation(DOL)were classified as the case group,and the remaining 60 patients with normal lactation were classified as the control group.The risk factors leading to DOL in GDM patients were summarized,and the correlation between glycolipid metabolism and DOL was analyzed.The specific nutritional intervention strategies were discussed.Results Pregnancy BMI≥28 kg/m2,pregnancy weight gain value ≥5 kg,primipara,cesarean section,fasting blood glucose(FBG)≥ 10 mmol/L,2h postprandial blood glucose(2h PG)≥13 mmol/L,glycated hemoglobin(HbA1c)≥10％,triglyceride(TG)≥2.50mmol/L,total cholesterol(TC)≥6.45 mmol/L,high-density lipoprotein cholesterol(HDL-C)≤1.80 mmol/L,low-density lipoprotein cholesterol(LDL-C)≥2.0 mmol/L,ApoA5≤100 µg/L,C1q/tumor necrosis factor associated protein 6(CTRP6)≥600 μg/L,and lack of systematic breastfeeding guidance were the risk factors for DOL in GDM.The incidence of DOL was positively correlated with FBG,2h PG,HbA1c,TG,TC,LDL-C,and CTRP6,and negatively correlated with HDL-C and ApoA5.Conclusion Overweight or obese primiparous women have a higher risk of DOL after delivery after Caesarean section,and its incidence is closely related to the function of glucose and lipid metabolism.A comprehensive assessment of the patient's nutritional status,individualized nutrition management,and corresponding breastfeeding guidance are of positive significance to prevent DOL and improve the rate of breastfeeding.
万方数据
维普
