Predictive value of physical activity in pregnancy on the prevalence of diabetes in pregnancy and its influence on blood sugar level
Objective To observe the correlation between physical activity during pregnancy and maternal blood glucose levels,and its predictive value for gestational diabetes mellitus(GDM).Methods Retrospective analysis of clinical data from 118 pregnant women who were placed on file for delivery in our hospital from June 2022 to June 2023 was performed.Based on the follow-up results during pregnancy,38 pregnant women diagnosed with GDM were classified as the case group,and the remaining normal pregnant women were classified as the healthy group.The pregnancy blood glucose levels and physical activity of the two groups of pregnant women were compared,and the correlation between physical activity and blood glucose levels was tested using the spearman correlation coefficient.The general and clinical data of two groups of parturients were compared,and the risk factors that can lead to GDM were summarized through statistical univariate analysis and logistic multiple regression analysis,the predictive value of physical activity during pregnancy on the risk of GDM was verified by plotting receiver operator characteristic curve(ROC)and observing area under the curve(AUC).Results The fasting blood glucose(FBG)and 2-hour postprandial blood glucose(2h PG)of the case group were(7.8±1.3)mmol/L and(12.3±3.4)mmol/L,respectively,which were higher than those of the healthy group[(6.4±1.3)mmol/L and(10.3±2.2)mmol/L].The total energy expenditure and physical activity of the case group were(4.4±1.3)METs/d and(175.3±20.5)MET h/week,respectively,which were lower than those of the healthy group[(5.9±1.9)METs/d and(191.5±20.4)MET h/week](P＜0.05).According to the spearman correlation coefficient test,the total energy expenditure and total physical activity during pregnancy are negatively correlated with FBG and 2h PG.The results of statistical univariate analysis showed that the proportion of cases in the case group with age≥30 years old,body mass index(BMI)≥24 kg/m2,FBG≥7 mmol/L,2h PG≥11 mmol/L,total energy expenditure ≤5 METs/d,total physical activity ≤180 MET h/week,total energy intake ≥2 000 kcal/d,carbohy-drate energy ratio ≥50％,fat energy ratio≥30％,and protein energy ratio ≤20％were higher than the healthy group(P＜0.05).The results of logistic multiple regression analysis showed that the risk factors for GDM were to-tal energy consumption ≤ 5 METs/d,total physical activity ≤180 MET h/week,total energy intake ≥2 000 kcal/d,total energy intake ≥2 000 kcal/d,carbohydrate energy ratio ≥50％,fat energy ratio ≥30％,and protein energy ratio ≤20％.According to the ROC curve test,the lower the total energy expenditure and physical activity during pregnancy,the higher the risk of GDM in pregnant women(AUC＞0.85).Conclusion The lower the physical activity during pregnancy,the higher the maternal blood sugar level.Monitoring parameters related to physical activity during pregnancy can to some extent achieve early prevention of GDM.
Physical expertionDiabetes,gestationalGlycemic indexiCorrelation of dataForecasting
万方数据
维普
