Etiological characteristics of 1 939 hospitalized children with acute respiratory tract infection in Xiamen in 2023
Objective To investigate the epidemiological characteristics of respiratory pathogens in children with acute respiratory infection(ARTI)in Xiamen in 2023.Methods A total of 1 939 throat swabs were collected from children with ARTI in Xiamen in 2023.Pathogens of influenza A(FluA),FluA-H1N1,FluA-H3N2,rhinovirus,respiratory syncytial virus(RSV),metapneumovirus,adenovirus(ADV),parainfluenza virus(PIV),human bocavirus(BoV),coronavirus,influenza B virus(FluB),mycoplasma pneumonia(MP),and chlamydia were detected.The detection data of 13 pathogens in the upper respiratory tract were analyzed.Results 75.66％of the children with ARTI were positive for at least one respiratory pathogen.Among different age groups,the school-age group had the highest positive detection rate of 13 respiratory pathogens(79.41％),followed by preschool children,early childhood children,and infant children(P＜0.05).PIV,RSV,and chlamydia infection tend to occur in infancy,with positive detection rates of 12.16％,23.87％,and 2.25％respectively.RVs and BoV infection occurred in early childhood,more positive detection rates of 25.13％and 3.54％respectively.ADV infection happened in the preschool period,more positive detection rate of 11.85％.FluA,FluA-H3N2,MP,and FluB infections mostly occurred in school-age children,with positive rates of 13.32％,8.13％,49.31％,and 7.79％,respectively(P＜0.05).The detection rates of FluA,FluA-H3N2,FluB,and MP pathogens increased with the age of the patients,and the detection rates of PIV and RSV pathogens decreased with the age of the patients(P＜0.05).FluA-H1N1 and RVs mainly occurred in spring,with positive detection rates of 12.80％and 21.48％,respectively.PIV and RSV mainly occurred in summer,with positive detection rates of 10.40％and 24.32％,respectively.FluA,FluA-H3N2,ADV,FluB,and chlamydia infections mostly oc-curred in winter,and the positive rates were 20.88％,17.78％,9.79％,14.95％and 1.80％,respectively(P＜0.05).Conclusion The prevalence of 13 respiratory pathogens in children with ARTI in Xiamen in 2023 is re-lated to gender,seasonality,and age stage,and the epidemic types of pathogens in different seasonality and age stages will appear alternately.Therefore,it is necessary to strengthen the monitoring of respiratory pathogens in children with ARTI and carry out accurate clinical treatment.
万方数据
维普
