摘要
目的 探索50岁及以上中老年人的身高、体质量、大腿长度、腰围和臀围五个体格指标与骨密度的相关性,对制定干预措施提供参考.方法 选取2017-2020年美国国家健康和营养调查数据库中50岁及以上体格指标与骨密度数据完整的2 072名调查人群作为研究对象.首先,将身高、体质量、大腿长度、腰围和臀围5个相关的体格指标利用结构方程模型"潜变量"生成过程进行降维处理;其次,将降维后生成的新变量Body_index、性别、种族作为自变量,分析其与全脊柱骨密度的相关性.结果 新变量Body_index与自变量身高、体质量、大腿长度、腰围和臀围进行多重线性拟合(R2为0.998),损失的信息＜2.0％.多重线性回归分析发现,可以认为新变量Body_index与全脊柱骨密度存在线性相关关系(P＜0.001),尚不能认为性别、种族与全脊柱骨密度存在线性关系(P＞0.05).结论 身材矮小、偏瘦为中老年人骨密度较低的危险因素,提示高危人群为防止骨质疏松、骨折,应适当增加体重,合理膳食.
Abstract
Objective To explore the correlation between five physical indicators,namely height,weight,thigh length,waist circumference,hip circumference,and bone mineral density in middle-aged and older adults aged 50 years and older,and to provide a reference for developing interventions.Methods A population of 2 072 surveyed individuals aged 50 and older with complete data on physical indicators and bone density form 2017-2020 National Health and Nutrition Examination Survey database was selected as the study population.First,five related physical indicators,namely height,weight,thigh length,waist circumference,and hip circumference,were downscaled using structural equation modeling(SEM)"latent variable"generation process.Second,Body_index,gender,and ethnicity,generated after the downscaling process,were used as the independent variables to analyze the correlation between them and total spinal bone mineral density(BMD).Results The new variable Body_index was fitted to the independent variables height,weight,thigh length,waist circumference,and hip circumference in a multiple linear fit(R2 of 0.998)with less than 2.0％loss of information.Multiple linear regression analysis revealed that the new variable Body_index could be considered to have a linear correlation with total spinal BMD(P＜0.001)and that gender and race could not yet be considered to have a linear relationship with total spinal BMD(P＞0.05).Conclusion Short stature and thinness are risk factors for low BMD in middle-aged and elderly people,suggesting that high-risk groups should increase their body weight appropriately and eat a reasonable diet to prevent osteoporosis and fractures.
基金项目
山西中医药大学博士科研启动基金项目(2023BK27)
山西省中医药管理局项目(20232YYB2034)
万方数据