Clinical study on collagen sponge combined with concentrated growth factor filled bone cavity after apical cyst surgery
Objective To investigate the effect of collagen sponge combined with concentrated growth factor on bone defects after apical cyst surgery.Methods A total of 60 patients were randomly divided into the experimental group and the control group(30 cases each).Collagen sponge infiltrated with concentrated growth factor(CGF)exudate was filled into the bone cavity remaining of experimental group,and the surface was covered with CGF membrane,no filling was placed in the control group.The degree of postoperative swelling,mouth opening degree and pain index were measured and recorded before and after operation.Cone beam computed tomography(CBCT)was performed at immediately,and 1、3、6 months post-surgery,and the keratinized gingiva width was measured at immediately,and 1、3、6 months post-surgery.The changes of clinical and CBCT data were compared between two groups.Results Three months after operation,there were significant differences between the two groups in the decreased alveolar bone and the keratinized gingiva width(P＜0.05).And six months after operation,there was significant differences in the keratinized gingiva width between the the experimental group and the control group(P＜0.05).There were significant differences between the two groups in postoperative swelling and pain index(P＜0.05).Conclusion The occurrence of postoperative swelling,pain and other adverse reactions could be reduced by implanting medical collagen and concentrated growth factor in the bone cavity,which can promote osteogenesis and reduce the absorption of the attached gum.
万方数据
维普
