Effect of neoadjuvant chemotherapy on myosonant effect of benzyl catracurium in patients with breast cancer
Objective To analyze the effect of neoadjuvant chemotherapy on the myosonant effect of benzyl catracurium in breast cancer patients.Methods Retroretrospective analysis of 72 breast cancer patients admitted to our hospital from January 2018 to December 2018,with ASA grade Ⅰ or grade,30 to 60 years old,body quality index(BMI)of 18 to 29 kg/m2.Patients were assigned to two groups after receiving neoadjuvant chemotherapy before surgery,38 cases in observation group(received neoadjuvant chemotherapy)and 34 cases in control group(no received neoadjuvant chemotherapy).Comparison of muscle relaxation,changes in physical signs,use of benzene and atracurium,rate of average infusion and adverse reactions.Results Heart rate,MAP and SpO2 sign levels at t1,t2,t3,t4,t5,t6 and RI time data showed no difference between the two groups(P＞0.05);The use of atracuronium decreased from 0 to 90 min in both groups,but the use of atracuronium at 0 to 30 min,31 to 60 min and 61 to 90 min was more than that of the control group,and the average infusion rate of the observation group was higher than that of the control group(P＜0.05);There was no difference in the incidence of adverse effects between the two groups(P＞0.05).Conclusion In patients with neoadjuvant chemotherapy,the average infusion rate of benzyl catracurium was large and the amount increased.
Breast cancerNeoadjuvant chemotherapyBenzyl catracuriumMyosonant effect
万方数据
维普
