[指示性摘要]单细胞测序提供了全方位理解肿瘤的方法.单细胞测序因不同的原理分为多种类型,它能够检测到单细胞的精细差异,甚至发现新的细胞类型,用于分析肿瘤的细胞谱系、基因图谱、克隆进化、免疫进化、肿瘤亚型和药物反应.单细胞测序正在改变我们对肿瘤的理解.
Single-cellanalysesprovideafundamentalunderstandingofcancer.Single-cellsequencinghasvarious typesaccordingtoprinciplesandrevealsthesubtlechangesthatmakeeachoneunique.Itcanevenrevealentirely newcelltypes.Single-cellsequencingcananalysecancercelllineagetrading,geneprofiles,clonalrevolution,im﹣munerevolution,cancersubtypesanddrugresponse.Single-cellanalysesaretransformingourunderstandingofhu﹣mancancers.