首页|肝癌合并门静脉癌栓的早期诊断

肝癌合并门静脉癌栓的早期诊断

扫码查看
肝细胞癌(hepatocellular carcinoma,HCC)是世界范围内最常见的原发性肝癌,也是慢性肝病患者常见的恶性肿瘤之一。在晚期诊断时,它通常与门静脉癌栓(portal vein tumor thrombus,PVTT)相关,这严重影响患者的预后。因此,早期检测PVTT对肝癌患者预后至关重要。PVTT预测模型是快速识别HCC伴PVTT高危人群的重要手段。彩色多普勒超声(CDUS)和超声造影(CEUS)是一种无创且易于重复的方法,能实时提供门静脉血流动态情况。计算机断层扫描(CT)和磁共振(MRI)是主要的诊断工具,在鉴别诊断良性血栓与恶性血栓中发挥重要作用。通过以上诊断方式以及利用生物学标志物的提示,实现HCC合并PVTT早期精准的诊断,从而达到早治疗的目的。
Early diagnosis of portal vein tumor thrombus in hepatocellular carcinoma
Hepatocellular carcinoma(HCC)is the most common primary liver cancer worldwide and one of the most common malignancies in patients with chronic liver disease.When diagnosed at an advanced stage,it is usually associ-ated with portal vein tumor thrombus(PVTT),which severely affects patient prognosis.Therefore,early detection of PVTT is crucial for the prognosis of patients with hepatocellular carcinoma.PVTT prediction model is an important tool for rapid identification of high-risk individuals with HCC combined with PVTT.Color Doppler ultrasound(CDUS)and ultrasonography(CEUS)are noninvasive and easily reproducible methods that provide real-time infor-mation on the dynamics of portal venous flow.Computed tomography(CT)and magnetic resonance imaging(MRI)are the main diagnostic tools that play an important role in the differential diagnosis of benign versus malignant thrombus.Through the above diagnostic modalities as well as the use of biological markers,the early and accurate di-agnosis of HCC combined with PVTT can be realized and the goal of early treatment can be achieved.

hepatocellular carcinomaportal vein tumor thrombusimaging diagnosisbiomarkersearly diagnosis

王欢、程树群

展开 >

广东药科大学第一临床医学院,广东 广州 510000

海军军医大学第三附属医院,上海 200438

肝细胞癌 门静脉癌栓 影像学诊断 生物标志物 早期诊断

2025

现代肿瘤医学
中国抗癌协会 陕西省抗癌协会 陕西省肿瘤防治研究所 陕西省医学会

现代肿瘤医学

影响因子:0.914
ISSN:1672-4992
年,卷(期):2025.33(1)