中晚期肺癌患者中医证候分布特点研究
Approach to distribution characteristics of TCM syndromes of patients with medium and advanced lung cancer
郭学泉 1冯淬灵 2穆新林 2杨嘉颐 2梁红格 2暴婧 2王克强 2冯枫 2孟玉凤 2张荣棋3
作者信息
- 1. 河南省郑州市第二人民医院(郑州450006)
- 2. 北京大学人民医院
- 3. 北京中医药大学
- 折叠
摘要
目的:探讨中晚期肺癌患者中医证候分布特点.方法:选取191例合格中晚期肺癌患者,设计《中晚期肺癌患者中医证候表》,按标准对患者的中医证候进行评定.分析中医证候、虚实证候、脏腑证候定位分布情况,中医证候及虚实证候在不同性别、年龄、TNM分期等方面的分布特点.结果:(1)虚实夹杂证频数占比最高(P＜0.01).(2)脾虚证与血瘀证比较,差异有统计学意义(P＜0.01);脾虚证、痰证、血瘀证分别与其他11种单种证候比较,差异有统计学意义(P＜0.05或P＜0.01).(3)肺病证候与其他4种单种常见脏腑证候比较,差异有统计学意义(P＜0.01).(4)单种中医证候实证＜60岁年龄段频数高于≥60岁(P＜0.01);虚证≥60岁年龄段频数高于＜60岁(P＜0.05).(5)Ⅳ期组在脾虚证、气虚证频数发生率上均明显高于Ⅲ期组(P＜0.05).结论:中晚期肺癌患者主要以虚实夹杂证为主,脾虚证、痰证、血瘀证最为常见.发病与肺脏、脾脏密切相关.实证多发生在＜60岁,虚证多发生在≥60岁.
Abstract
Objective:To approach the distribution characteristics of TCM syndromes of patients with medium and advanced lung cancer.Methods:191 cases of patients with medium and advanced lung cancer were selected.TCM Syndromes Table for Patients with Medium and Advanced Lung Cancer was designed.TCM syndromes of the patients were evaluated according to the standard.The localizing distributions of TCM syndromes,deficiency-excess syndromes and viscera syndromes were analyzed,and the distribution characteristics of TCM syndromes and deficiency-excess syndromes of different gender,age and TNM staging,etc.were apporached.Results:1.The frequency of syndrome of deficiency mingling with excess was the highest(P＜0.01).2.Compared the frequency of spleen deficiency syndrome with frequency of blood stasis syndrome,the difference was statistically significant(P＜0.01).Compared the frequencies of spleen deficiency syndrome,phlegm syndrome and blood stasis syndrome respectively with frequencies of other 11 single-syndromes,the differences were statistically significant(P＜0.05 or P＜0.01).3.Compared the lung disease syndrome with other four common syndromes of viscera,the difference was statistically significant(P＜0.01).4.The frequency of excess syndrome of＜age group of 60 years old was higher than that of ≥age group of 60 years old(P＜0.01).The frequency of deficiency syndrome of ≥ age group of 60 years old was higher than that of＜age group of 60 years old(P＜0.05).5.The frequencies of spleen deficiency syndrome and qi deficiency syndrome in the group of stage Ⅳ was significantly higher than that in the group of stage Ⅲ(P＜0.05).Conclusion:In the patients with medium and advanced lung cancer,the syndrome of deficiency mingling with excess is main,and spleen deficiency syndrome,phlegm syndrome and blood stasis syndrome are the.most common.The pathogenesis is closely related to the lung and spleen.The excess syndrome occurs mostly in＜60 years old,while the deficiency syndrome occurs mostly in ≥ 60 years old.
关键词
肺癌/中医证候/分布特点Key words
lung cancer/TCM syndrome/distribution characteristics引用本文复制引用
基金项目
北京大学人民医院自主选题项目(2021PHB151-001)
出版年
2024
NETL
NSTL
维普
万方数据