首页|补肾活血方治疗肾虚血瘀型老年性骨质疏松症临床观察

补肾活血方治疗肾虚血瘀型老年性骨质疏松症临床观察

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目的:观察补肾活血方联合阿仑膦酸钠维D3片治疗肾虚血瘀型老年性骨质疏松症的临床疗效。方法:将64例肾虚血瘀型老年性骨质疏松症患者随机分为两组各32例。对照组予口服阿仑膦酸钠维D3片治疗,治疗组在对照组基础上予补肾活血方治疗。观察治疗前后两组患者的腰背部疼痛评分、骨密度指标、血清白介素-6水平及临床证候积分,判断其临床疗效。结果:两组患者的腰背部疼痛评分及白介素-6水平均较治疗前下降(P<0。05),且治疗组下降程度均优于对照组(P<0。05);两组患者的骨密度水平均较治疗前升高(P<0。05),且治疗组升高程度优于对照组(P<0。05);治疗后治疗组总有效率为93。75%,优于对照组的81。25%,差异具有统计学意义(P<0。05)。结论:补肾活血方联合阿仑膦酸钠维D3片治疗肾虚血瘀型老年性骨质疏松症的疗效确切,且优于单纯西医治疗。
Efficacy observation of Bushen Huoxue formula on senile osteoporosis with syndrome of kidney deficiency and blood stasis
Objective:To observe the clinical efficacy of Bushen Huoxue formula and alendronate sodium vitamin D3 tablets on senile osteoporosis with syndrome of kidney deficiency and blood stasis.Methods:64 cases of patients with senile osteoporosis with syndrome of kidney deficiency and blood stasis were randomly divided into two groups,32 cases in each group.The control group was treated with oral alendronate sodium vitamin D3 tablets,while the treatment group was treated plus with Bushen Huoxue formula on the basis of control group.Low back pain score,bone mineral density index,serum interleukin-6 level and clinical symptom score of patients were observed in two groups before and after treatment,and the clinical efficacy was evaluted.Results:Low back pain score and interleukin-6 level of patients were decreased in two groups compared with those before treatment(P<0.05),and the degree of decrease in the treatment group was larger than that in the control group(P<0.05).The level of bone mineral density of patients in both groups was increased compared with that before treatment(P<0.05),and the degree of increase in the treatment group was larger than that in the control group(P<0.05).After treatment,the total effective rate of treatment group was 93.75%,which was better than 81.25%of control group,and the difference was statistically significant(P<0.05).Conclusion:The clinical efficacy of Bushen Huoxue formula and alendronate sodium vitamin D3 on senile osteoporosis with syndrome of kidney deficiency and blood stasis is definite,and better than that of simple western medicine.

senile osteoporosiskidney deficiency and blood stasisBushen Huoxue formulaintegrated therapy of traditional Chinese and western medicine

卢博成、孙绍裘

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湖南中医药大学第二附属医院(长沙410005)

老年性骨质疏松 肾虚血瘀 补肾活血方 中西医结合疗法

湖南省临床医疗技术创新引导项目孙达武名老中医工作室项目湖南省教育厅科研项目

2021SK513012020SK4013

2024

山西中医
山西省中医药学会 山西中医药研究院

山西中医

影响因子:0.59
ISSN:1000-7156
年,卷(期):2024.40(4)
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