Efficacy observation of Yiqi Jianpi Tongbian formula and acupoint application on slow transit constipation
Objective:To observe the clinical efficacy of Yiqi Jianpi Tongbian formula and acupoint application on slow transit constipation.Methods:60 cases of patients with slow-transit constipation were selected and randomly divided into two groups,30 cases in each group.The control group was treated with prucalopride succinate,while the treatment group was treated with Yiqi Jianpi Tongbian formula and acupoint application.Clinical efficacy,scores of quality of life,excretion amount of markers in large intestine and changes of content of serum nitric oxide(NO)and level of peptide neurotransmitters(SP)were observed in two groups.Results:The total clinical effective rate of treatment group was 93.33％,which was higher than 83.33％of control group.After treatment in both groups,self-score of life-quality of patients was decreased compared with before treatment(P＜0.05),and the decrease of treatment group was more significant(P＜0.05).After treatment in both groups,the excretion amount of markers in large intestine of patients was significantly increased after 48 hours and 72 hours compared with at the same time point before treatment(P＜0.05),and the increase in the treatment group was more significant than in the control group.(P＜0.05);the level of peptide neurotransmitters(SP)of patients was increased in both groups(P＜0.05),while the content of serum nitric oxide was decreased(P＜0.05),and the improvement of SP level and NO content in the treatment group was better than that in the control group(P＜0.05).Conclusion:The clinical efficacy of Yiqi Jianpi Tongbian formula and acupoint application on slow transit constipation is better.
slow transit constipationYiqi Jianpi Tongbian formulaacupoint applicationtherapy of TCM
NETL
NSTL
万方数据
维普
