Efficacy observation of Huangqin decoction and chemotherapy on colorectal cancer with syndrome of toxin generated by accumulation of damp-heat
Objective:To observe the clinical efficacy of modified Huangqin decoction and chemotherapy on colorectal cancer with syndrome of toxin generated by accumulation of damp-heat.Methods:60 cases of eligible patients with colorectal cancer were selected and randomly divided into two groups,30 cases in each group.The control group was treated by chemotherapy of mFOLFOX6 regimen,while the treatment group was treated plus with modified Huangqin decoction on the basis of control group.Levels of CEA and CA199 of tumor marker,immune function,score of syndrome of toxin generated by accumulation of damp-heat,KPS score and safety evaluation,etc.were compared between two groups.Results:After treatment,CD3+,CD4+,CD4+/CD8+and KPS score of treatment group were higher than those of control group(P＜0.05).The levels of CEA,CA199 and CD8+,the score of syndrome of toxin generated by accumulation of damp-heat and the incidence rat of toxic and side reactions in the treatment group were lower than those in the control group(P＜0.05).Conclusion:The clinical efficacy of modified Huangqin decoction and chemotherapy on colorectal cancer with syndrome of toxin generated by accumulation of damp-heat is better,which can assist the chemotherapy,so as to increase the clinical efficacy of anti-colorectal cancer,improve the clinical symptoms and enhance the immune function of the body.
colorectal cancermodified Huangqin decoctiontherapy of TCM
NETL
NSTL
万方数据
维普
