首页|芪葛威灵胶囊治疗糖尿病周围神经病变临床观察

芪葛威灵胶囊治疗糖尿病周围神经病变临床观察

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目的:观察芪葛威灵胶囊治疗气阴两虚兼血瘀型糖尿病周围神经病变患者的临床疗效。方法:选取120例气阴两虚兼血瘀型糖尿病神经病变患者,按随机数字表法分为两组各60例。治疗组予芪葛威灵胶囊治疗,对照组予甲钴胺片口服。治疗8周后,比较两组患者临床疗效、中医证候积分、多伦多临床评分系统(TCSS)评分、神经传导速度、不良反应等。结果:治疗组总有效率91。67%,优于对照组的68。33%(P<0。05);治疗后,两组患者肢体麻木、疼痛及小腿抽搐证候积分均明显下降(P<0。05),两组TCSS评分均明显降低(P<0。05),腓总神经、胫后神经运动神经传导速度均明显提高(P<0。05),且治疗组改善程度均优于对照组(P<0。05)。结论:芪葛威灵胶囊可改善气阴两虚兼血瘀型糖尿病周围神经病变患者的临床症状,提高TCSS评分、改善神经传导速度,临床疗效良好。
Efficacy observation of Qige Weiling capsule on diabetic peripheral neuropathy
Objective:To observe the clinical efficacy of Qige Weiling capsule on diabetic peripheral neuropathy with syndrome of deficiency of both qi and yin intermingled with blood stasis.Methods:120 cases of patients with diabetic peripheral neuropathy with syndrome of deficiency of both qi and yin intermingled with blood stasis were selected and randomly divided into two groups,60 cases in each group.The treatment group was treated with Qige Weiling capsule,while the control group was treated with oral mecobalamin tablets.Clinical efficacy,TCM syndrome score,Toronto Clinical Scoring System(TCSS)score,nerve conduction velocity and adverse reactions etc.of patients were compared between two groups after 8 weeks of treatment.Results:The total effective rate of treatment group was 91.67%,which was better than 68.33%of control group(P<0.05).After treatment in both groups,the syndrome scores of numbness and pain of limbs as well as calf convulsions of patients were decreased significantly(P<0.05);TCSS scores were decreased significantly(P<0.05);the motor nerve conduction velocities of common peroneal nerve and posterior tibial nerve were significantly increased;and the improvement of treatment group was better than that of control group(P<0.05).Conclusion:Qige Weiling capsule can improve the clinical symptoms of patients with diabetic peripheral neuropathy with syndrome of deficiency of both qi and yin intermingled with blood stasis,increase TCSS score,and improve nerve conduction velocity.Its clinical efficacy is better.

Qige Weiling capsulediabetic peripheral neuropathytherapy of TCM

闫冬雪、孟永杰、郭晓霏、杨丽丽、刘亚丽、郭俊杰

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山西省中医院(太原030012)

河北中医药大学

芪葛威灵胶囊 糖尿病周围神经病变 中医药疗法

2024

山西中医
山西省中医药学会 山西中医药研究院

山西中医

影响因子:0.59
ISSN:1000-7156
年,卷(期):2024.40(6)