首页|益肾解毒化瘀方治疗慢性肾脏病合并动脉粥样硬化临床观察

益肾解毒化瘀方治疗慢性肾脏病合并动脉粥样硬化临床观察

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目的:观察益肾解毒化瘀方对慢性肾脏病3~4期合并动脉粥样硬化患者的临床疗效。方法:选取符合纳入标准的脾肾气虚兼血瘀型慢性肾脏病3~4期合并动脉粥样硬化患者60例,随机分为两组各30例。对照组采用慢性肾脏病一体化治疗,治疗组在对照组基础上加用益肾解毒化瘀方。治疗12周后比较两组临床疗效。结果:治疗组临床总有效率为90。0%,明显高于对照组的76。7%(P<0。05);治疗后,治疗组Scr、BUN、Ccr、LDL-C、TG、RDW、CRP、UA、IMT水平改善程度均优于对照组(P<0。05),治疗组斑块面积、总证候积分均优于对照组(P<0。05)。结论:益肾解毒化瘀方治疗脾肾气虚兼血瘀型慢性肾脏病3~4期合并动脉粥样硬化患者可以有效改善患者肾功能及临床症状,降低RDW水平。
Efficacy observation of Yishen Jiedu Huayu formula on chronic kidney diseases complicated with atherosclerosis
Objective:To observe the clinical efficacy of Yishen Jiedu Huayu formula on chronic kidney disease complicated with atherosclerosis in stage 3-4.Methods:60 cases of eligible patients with chronic kidney disease complicated with atherosclerosis in stage 3-4 and with syndrome of qi deficiency of spleen and kidney intermingled with blood stasis were selected and randomly divided into two groups,30 cases in each group.The control group was treated by systematic treatment model for chronic kidney disease,while the treatment group was treated plus with Yishen Jiedu Huayu formula on the basis of control group.The clinical efficacy was compared between two groups after 12 weeks of treatment.Results:The total clinical effective rate of treatment group was 90.00%,which was significantly higher than 76.70%of control group(P<0.05).In the treatment group after treatment,the improvement of levels of Scr,BUN,Ccr,LDL-C,TG,RDW,CRP,UA and IMT was better than in the control group(P<0.05),and the plaque area and total syndrome score were better than in the control group(P<0.05).Conclusion:Yishen Jiedu Huayu formula for treating chronic kidney disease complicated with atherosclerosis in stage 3-4 and with syndrome of qi deficiency of spleen and kidney intermingled with blood stasis can effectively improve the renal function and clinical symptoms of patients,and reduce RDW level.

chronic kidney diseaseatherosclerosisYishen Jiedu Huayu formulatherapy of TCM

万鸣宏、陈美雪、蓝小琴、于清志、吴晓芸

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浙江省平湖市中医院(平湖314200)

慢性肾脏病 动脉粥样硬化 益肾解毒化瘀方 中医药疗法

浙江省平湖市科技计划项目

社发类2023-6号

2024

山西中医
山西省中医药学会 山西中医药研究院

山西中医

影响因子:0.59
ISSN:1000-7156
年,卷(期):2024.40(9)