Analysis of distribution rule of TCM syndromes of rheumatoid arthritis and differences of erythrocyte sedimentation rate and C-reactive protein of different syndromes types
Objective:To analyze the distribution rule of TCM syndromes of rheumatoid arthritis and differences of erythrocyte sedimentation rate(ESR)and C-reactive protein of different syndromes.Methods:The cross-sectional data of 500 patients with rheumatoid arthritis were included.The correlativity between different TCM syndrome types of rheumatoid arthritis and age,gender,course of disease,comorbidity of cardiovascular disease,erythrocyte sedimentation rate and C-reactive protein were analyzed statistically.Results:1.Compared with the group of≤60 years old,syndrome of deficiency of liver and kidney and syndrome of deficiency of both qi and yin were more in the group of>60 years old,while syndrome of wind-dampness obstruction and syndrome of deficiency of both qi and blood were less(P<0.05).2.Compared with male group,syndrome of wind-dampness obstruction,syndrome of cold-dampness obstruction and syndrome of deficiency of both qi and blood were more in female group,while syndrome of damp-heat obstruction and syndrome of blood-stasis obstruction in collaterals were less(P<0.05).3.Compared with the group with disease course>15 years,for the disease course≤5 years and 6-15 years,syndrome of phlegm-blood stasis obstruction was less,while syndrome of wind-dampness obstruction was more(P<0.05).Compared with the group with disease course≤5 years,for the disease course for 6-15 years,syndrome of wind-dampness obstruction was less(P<0.05).4.Compared with the group with non-comorbidity of cardiovascular disease,in the group with comorbidity of cardiovascular disease,syndrome of phlegm-blood stasis obstruction and syndrome of deficiency of liver and kidney were more,while syndrome of wind-dampness obstruction was less(P<0.05);5.Compared with syndrome of phlegm-blood stasis obstruction,the median of erythrocyte sedimentation rate of syndrome of wind-dampness obstruction and syndrome of deficiency of both qi and blood was lower(P<0.05).Compared with syndrome of deficiency of both qi and blood,the median of C-reactive protein of syndrome of damp-heat obstruction,syndrome of phlegm-blood stasis obstruction and syndrome of deficiency of both qi and yin was higher(P<0.05).Compared with syndrome of wind-dampness obstruction,the median of C-reactive protein of syndrome of damp-heat obstruction,syndrome of phlegm-blood stasis obstruction and syndrome of deficiency of both qi and yin was higher(P<0.05).Conclusion:There are significant differences between different TCM syndrome types of rheumatoid arthritis and gender,age,course of disease,comorbidity of cardiovascular disease,erythrocyte sedimentation rate and C-reactive protein.