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当归补血汤治疗脾肾气虚型肾性贫血临床观察

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目的:观察当归补血汤治疗脾肾气虚型肾性贫血的临床疗效。方法:选取符合纳入标准的脾肾气虚型肾性贫血患者60例,采用随机数字表法分为两组各30例。对照组予重组人促红素注射液皮下注射,治疗组在对照组基础上予当归补血汤。比较两组治疗前及治疗4、8周贫血指标、微炎症水平、肾功能、中医证候积分及临床疗效。结果:治疗4周、8周,治疗组总有效率分别为86。67%、100%,对照组总有效率分别为80。00%、86。67%,治疗组高于对照组(P<0。05)。治疗4周、8周两组Hb、HCT、MCV、GFR均上升(P<0。05),CRP、Scr、BUN、中医证候积分均降低(P<0。05),且治疗组优于对照组(P<0。05)。结论:当归补血汤治疗脾肾气虚型肾性贫血临床效果明显,能有效改善患者贫血及肾功能指标、微炎症水平,改善中医证候。
Efficacy observation of Danggui Buxue decoction on renal anemia with syndrome of deficiency of both spleen-qi and kidney-qi
Objective:To observe the clinical efficacy of Danggui Buxue decoction on renal anemia with syndrome of deficiency of both spleen-qi and kidney-qi.Methods:60 cases of eligible patients with renal anemia with syndrome of deficiency of both spleen-qi and kidney-qi were selected and randomly divided into two groups,30 cases in each group.The control group was subcutaneously injected recombinant human erythropoietin injection,while the treatment group was treated plus with Danggui Buxue decoction on the basis of control group.Anemia indexes,micro-inflammatory level,renal function,TCM syndrome score and clinical efficacy were compared between two groups before treatment and after treatment for 4 and 8 weeks.Results:After 4 and 8 weeks of treatment,the total effective rate of treatment group was 86.67%and 100%respectively,while the total effective rate of control group was 80.00%and 86.67%respectively,and the treatment group was higher than control group in total effective rate(P<0.05).In both groups after 4 and 8 weeks of treatment,Hb,HCT,MCV and GFR were increased(P<0.05),while CRP,Scr,BUN and TCM syndrome scores were decreased(P<0.05),and the treatment group was better than control group(P<0.05).Conclusion:The clinical efficacy of Danggui Buxue decoction on renal anemia with syndrome of deficiency of both spleen-qi and kidney-qi is significant,which can effectively improve the indexes of anemia and renal function,micro-inflammation level and TCM syndrome of parients.

renal anemiaDanggui Buxue decoctionintegrated therapy of traditional Chinese and western medicine

石艳霞、魏彦宁、宋丽

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宁夏回族自治区银川市中医医院(银川750001)

肾性贫血 当归补血汤 中西医结合疗法

2024

山西中医
山西省中医药学会 山西中医药研究院

山西中医

影响因子:0.59
ISSN:1000-7156
年,卷(期):2024.40(12)