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肠道菌群在中医药治疗哮喘中的机制研究进展

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哮喘是一种以反复喘息、气促、胸闷、咳嗽为特征的疾病,具体发病机制目前尚未明确,西医无治愈哮喘的有效方法,肠道菌群通过与代谢产物、免疫系统以及肠黏膜屏障等相互作用影响哮喘发病,成为近年研究的热点之一.中医学从气机升降、水液代谢等角度,以脏腑辨证为立足点,发现中医药可通过调节肠道菌群及代谢产物减轻哮喘症状,在防治哮喘中有较大潜力.因此,深入研究揭示中医药治疗哮喘的作用机制,可为临床治疗及基础研究提供新思路.
Research Progress on the Mechanism of Gut Microbiota in the Treatment of Asthma with Traditional Chinese Medicine
Asthma is a disease characterized by repeated wheezing,shortness of breath,chest tightness,and coug-hing.The specific pathogenesis is currently unclear,and Western medicine has no effective method to cure asthma.The gut microbiota affects the onset of asthma through interactions with metabolites,the immune system,and the intestinal mu-cosal barrier,making it one of the research hotspots in recent years.Traditional Chinese Medicine(TCM),based on the differentiation of internal organs,has found that TCM can alleviate asthma symptoms by regulating gut microbiota and meta-bolic products,and has great potential in the prevention and treatment of asthma.Therefore,in-depth research to reveal the mechanism of action of traditional Chinese medicine in treating asthma can provide new ideas for clinical treatment and bas-ic research.

AsthmaGut microbiotaMetabolitesTraditional Chinese medicineMucosal immunity

邱丹丹、杨一民、李蕙、虞雅颖

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北京中医药大学厦门医院儿科,福建厦门 361000

北京中医药大学第一临床医学院,北京 100000

哮喘 肠道菌群 代谢产物 中医药 黏膜免疫

2025

现代中医药
陕西中医学院 中华中医药学会

现代中医药

影响因子:0.487
ISSN:1672-0571
年,卷(期):2025.45(1)