Effect of Single-housing and Pair-housing on Hematological and Biochemical Parameters,Ethology and Immune Stress of Cynomolgus monkeys
Objective To investigate the effects of single housing and pair housing on hematological and biochemical parameters,behavior,and immune stress indices of cynomolgus monkeys.Method 3 years old cynomolgus monkeys,4 males and 4 females,were separated and pair housing by sex.Blood samples were collected at acclimation period,D14 and D21 of single housing and pair housing for hematological,biochemical and immune stress analysis.Behavioral observation was performed during D14 to D21 of single housing and pair housing.Result There was no significant difference in hematological and immune stress indexes of cynomolgus monkeys between single housing and pair housing.In terms of serum biochemistry,compared with the base value,TBIL decreased significantly after pair housing,LDH decreased significantly during single housing.The normal and positive behaviors increased by 27.93%and 86.10%respectively,and abnormal behaviors decreased by 26.31%in cynomolgus monkeys after pair housing.Conclusion The result showed that single housing or pair housing for cynomolgus monkeys had no significant effect on hematological and immune stress indexes.LDH decreased in single housing and TBIL decreased in pair housing,but they were all within the normal background values.The abnormal behaviors of captive cynomolgus monkeys and animal welfare were effectively improved by paired housing.
万方数据
维普
