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基于科研范式变革的实验动物资源创新发展

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实验动物是支撑生命科学和生物医药等领域科技创新的重要基础科研条件之一.随着科研范式的变革,准确把握科学前沿和国家重大需求,进一步凝练实验动物资源创制与发展中的难点和疑点,对加快推动实验动物新品种/新品系开发和动物模型创制与发展具有重要意义.本文梳理了我国实验动物资源建设和应用情况,就应对新形势下的科研范式变革中存在的主要问题进行了深入探讨,展望了我国实验动物资源发展新动向,以期为实验动物新资源研究开发提供新视角.
Reflection on the Innovation and Development of Laboratory Animal Resources Based on the Transformation of Scientific Research Paradigm
Laboratory animals are one of the important basic research conditions that support technological innovation in fields such as life sciences and biomedicine.With the transformation of scientific research paradigms,accurately grasping the forefront of science and major national needs,further refining the difficulties and doubts in the creation and development of laboratory animal resources,is of great significance for accelerating the development of new varieties/strains of laboratory animals and animal model creation and development.The paper reviews the construction and application of laboratory animal resources in China,and deeply explores the main problems in responding to the transformation of scientific research paradigms under the new situation.It also looks forward to new trends in the development of experimental animal resources in China,in order to provide a new perspective for the research and development of new experimental animal resources.

laboratory animalsanimal modelsresearch paradigmproblem condensationinnovative thinkingnew perspective

贺争鸣、陈洪岩、陈振文、孙岩松、巩薇、梁春南

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中国食品药品检定研究院,北京 102629

中国农业科学院哈尔滨兽医研究所,哈尔滨 150069

首都医科大学,北京 100069

军事医学研究院,北京 100039

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实验动物 动物模型 科研范式 问题凝练 创新思维 新视角

国家科技基础条件平台中心

2022WT28

2024

实验动物科学
北京实验动物研究中心 北京实验动物学学会 北京实验动物管理办公室

实验动物科学

CSTPCD
影响因子:0.603
ISSN:1006-6179
年,卷(期):2024.41(1)
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