芍药苷抗炎作用机制研究进展
Research Progress on Anti-inflammatory Mechanisms of Paeoniflorin
刘馨鸿 1郭超 1宋冰 2赵泓彰 2王琼 2白敏 2宋文静 2张钰 3连源 3张延英 2赵兴绪1
作者信息
- 1. 甘肃农业大学动物医学院,兰州 730000
- 2. 甘肃中医药大学,兰州 730000;甘肃省实验动物行业技术中心,兰州 730000
- 3. 甘肃中医药大学,兰州 730000
- 折叠
摘要
炎性反应是对外界刺激的异常免疫反应,可导致多器官组织功能损伤障碍.中医学运用芍药治疗炎性反应已有近千年历史,芍药苷是从芍药干燥根中提取的主要天然活性成分,具有广泛的抗炎和免疫调节作用,临床应用潜力巨大.本文对芍药苷在抗炎作用机制以及研究现状予以综述,以期为芍药苷抗炎作用机制提供理论依据,也为芍药苷进一步的开发和应用提供参考.
Abstract
Inflammation is an abnormal immune response to external stimuli,which can lead to multi-organ tissue dysfunction.Paeoniflorin has been used in Chinese medicine to treat inflammation for nearly a thousand years.Paeoniflorin is the main natural active ingredient extracted from the dried root of Paeoniflorin.It has a wide range of anti-inflammatory and immunomodulatory effects,and has great clinical application potential.In this paper,the anti-inflammatory mechanism and research status of paeoniflorin were reviewed,in order to provide theoretical basis for the anti-inflammatory mechanism of Paeoniflorin and provide reference for further development and application of Paeoniflorin.
关键词
芍药苷/抗炎/机制/研究进展Key words
Paeoniflorin/anti-inflammatory/mechanism/research progress引用本文复制引用
基金项目
甘肃省优秀研究生创新之星项目(2023CXZX-670)
国家自然科学基金联合基金重点项目(U21A20262)
出版年
2024