Comparison on Molecular Typing Technologies and the Infection Condition of Staphylococcus Aureus in Laboratory Animals
Staphylococcus aureus(S.aureus)is a zoonotic opportunistic pathogen,which is must be monitored and excluded from the barrier environment and often is a serious threat to the quality of laboratory animals and the health of practitioners.It is critical to use accurate,sensitive,and rapid method of molecular typing to control the transmission of S.aureus in the laboratory animal barrier environment.The molecular method for typing S.aureus main including Staphylococcal cassette chromosome mec typing,Staphylococcal protein A typing,multilocus sequence typing,Pulsed field gel electrophoresis typing,accessory gene regulator typing,and others.Understand the infection status of Staphylococcus aureus in laboratory animals of barrier systems and comparation of the technical characteristics and applications of different molecular typing method,which can provide a reference for the detection and typing of Staphylococcus aureus of laboratory animal origin.
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