Construction and Evaluation of Mouse Depression Models
Depression has received widespread attention from the medical community due to its increasing incidence year by year.The factors of depression are extremely complex,so the construction of depression models has become a key step when conducting related experiments.This paper mainly introduces the construction method of common mouse depression models,such as chronic unpredictable mild stimulus model,special drug-induced depression model,early life stress model,etc.,and related behavioural experiments to assess the degree of depression,such as forced swimming experiment,sucrose preference experiment,splashing experiment,etc.,which provide relevant researchers with experimental ideas and method.