首页|类器官有望成为解决实验动物伦理问题的办法之一

类器官有望成为解决实验动物伦理问题的办法之一

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实验动物伦理问题一直是动物实验中不可忽视的问题,并越来越受关注.随着实验动物"3R"(替代、减少、优化)原则及各种保障实验动物福利法律法规的实施,发展实验动物替代技术势在必行.近年来各种类器官技术飞速发展,并展现出巨大优势,有望成为解决实验动物伦理问题的办法之一.本文综述了动物实验中存在的问题以及类器官的发展与应用,以期为实验动物替代技术的发展以及实验动物伦理问题的解决提供新的思路.
Organoids are Expected to be one of the Ethical Problems of Experimental Animals
The ethics of experimental animals has been a issue that cannot be ignored in animal experiments and attracts increasing attention.With the implementation of the"3R"(replacement,reduction,refinement)principle of experimental animals and various laws and regulations guaranteeing the welfare of experimental animals,it is imperative to develop the replacement technology of experimental animals.In recent years,various organoid technologies have developed rapidly and shown great advantages,which is expected to be one of the ways to solve the ethical problems of experimental animals.This paper summarizes the problems in animal experiments and the development and application of organoids,in order to provide new ideas for the development of replacement technology of experimental animals and solve the ethical problems of experimental animals.

organoidsanimal experimentsethics of experimental animalsreplacement techniques for experimental animals

任美丹、朱金墙

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天津中医药大学组分中药国家重点实验室,天津中医药大学方剂学教育部重点实验室,天津中医药大学中医药研究院,天津 301617

类器官 动物实验 实验动物伦理 实验动物替代技术

2024

实验动物科学
北京实验动物研究中心 北京实验动物学学会 北京实验动物管理办公室

实验动物科学

CSTPCD
影响因子:0.603
ISSN:1006-6179
年,卷(期):2024.41(6)