微血管血流成像技术评估复发性流产与正常育龄期女性子宫内膜微血流血管化指数差异的价值
The Value of Micro-Vascular Flow Imaging in Evaluating the Difference of En-dometrial Micro-Flow Vascularization Index between Recurrent Spontaneous Abortion and Normal Reproductive Age Women
于珍 1唐英 1秦茜羽1
作者信息
- 1. 四川大学华西第二医院超声科出生缺陷与相关妇儿疾病教育部重点实验室,四川成都 610041
- 折叠
摘要
目的:探讨微血管血流(MV-Flow)成像技术评估复发性流产女性与正常育龄期女性子宫内膜微血流血管化指数(ⅥMV)差异的临床价值.方法:选取2022年6月至2023年6月在四川大学华西第二医院就诊的87例不明原因的复发性流产患者作为流产组,其中流产次数为2次有51例,3次有26例,≥4次有10例;另选取于本院同期就诊的90例无流产史的正常育龄期女性作为健康组.两组女性于黄体中期时经阴道超声运用MV-Flow成像技术测量子宫内膜ⅥMV,并将177例女性的子宫内膜ⅥMV均值进行观察者内及观察者间的重复测量,比较两组子宫内膜ⅥMV及临床资料的差异;同时比较流产组中不同流产次数患者子宫内膜ⅥMV及临床资料的差异.结果:流产组患者的年龄、体质量指数、卵泡刺激素及黄体生成素与健康组比较,差异均无统计学意义(P＞0.05).健康组子宫内膜ⅥMV高于流产组,差异有统计学意义(6.10％vs.3.70％,P＜0.05).流产组中流产次数为2次(5.30％)的患者子宫内膜ⅥMV高于流产次数为3次(3.25％)及≥4次(3.30％)的患者,差异有统计学意义(P＜0.05),流产次数为3次的患者子宫内膜ⅥMV与≥4次的患者比较差异无统计学意义(P＞0.05).177例女性的子宫内膜ⅥMV均值在观察者内及观察者间的组内相关系数分别为0.978、0.945,重复性均较好.结论:MV-Flow成像技术可有效评估复发性流产女性与正常育龄期女性子宫内膜ⅥMV的差异,且可能随着流产次数的增多,子宫内膜ⅥMV也会随之降低.
Abstract
Objective:To investigate the clinical value of micro-vascular flow(MV-flow)imaging in evaluating the difference of endometrial micro-flow vascularization index(ⅥMV)between recurrent spontaneous abortion and normal reproductive age women.Methods:From June 2022 to June 2023,87 patients with unexplained recurrent spontaneous abortion in West China Second University Hospital,Sichuan University were selected as the abortion group,including 51 patients with 2 miscarriages,26 patients with 3 miscarriages,and 10 patients with≥4 miscar-riages.In addition,90 normal women of childbearing age who did not have a history of miscarriage and visited our hospital during the same period were selected as the healthy group.Endometrial ⅥMV was measured by transvag-inal ultrasound using MV-flow imaging technology in mid-luteal phase of the two groups.The mean values of en-dometrial ⅥMV in 177 women was measured repeatedly within and between observers.The endometrial ⅥMVand clinical data were compared between the two groups.The differences of endometrial ⅥMV and clinical data in pa-tients with different miscarriage times in the abortion group were compared simultaneously.Results:There was no statistically significant difference in age,body mass index,follicle stimulating hormone and luteinizing hormone be-tween the healthy group and the abortion group(P＞0.05).The ⅥMV of endometrium in healthy group was higher than that in abortion group,and the difference was statistically significant(6.10％vs.3.70％,P＜0.05).In the abortion group,endometrial ⅥMV in patients with 2 miscarriages(5.30％)was higher than that in patients with 3(3.25％)miscarriages and≥ 4(3.30％)miscarriages,and the difference was statistically significant(P＜0.05).There was no statistically significant difference in endometrial ⅥMV between patients with 3 miscarriages and ≥4 miscarriages(P＞0.05).The intraobserver and interobserver correlation coefficients of endometrial ⅥMV were 0.978 and 0.945,respectively.Conclusions:MV-flow imaging technology can effectively evaluate the difference of endometrial ⅥMV between recurrent spontaneous abortion and normal childbearing age women,and endometri-al ⅥMV may decrease with the increase of miscarriage frequency.
关键词
超声检查/微血管血流/复发性流产/子宫内膜微血流血管化指数Key words
Ultrasound examination/Micro-vascular flow/Recurrent spontaneous abortion/Endometrial mi-cro-flow vascularization index引用本文复制引用
出版年
2023
国家科技期刊平台
NSTL
维普
万方数据