首页|孕前腹腔镜子宫颈环扎术治疗子宫颈机能不全的临床疗效分析

孕前腹腔镜子宫颈环扎术治疗子宫颈机能不全的临床疗效分析

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目的:探讨孕前腹腔镜子宫颈环扎术(LCC)在改善子宫颈机能不全妊娠结局中的应用价值。方法:回顾性分析郑州大学第一附属医院2014 年7 月1 日至2023 年5 月31 日112 例子宫颈机能不全患者行孕前LCC的临床资料。其中孕前LCC手术指征为:经阴道子宫颈环扎术(TCC)失败(42 例)、子宫颈手术史+TCC失败(7 例)、不适合TCC(10 例)和患者强烈要求(53 例)。分析孕前LCC患者的手术情况及妊娠结局,对比孕前LCC 后妊娠并分娩的患者和因不同手术指征行孕前LCC患者手术前后的分娩孕周。结果:112 例患者中位手术时间 65。5 min、中位术中出血量 10。0 ml,无术中并发症,术后住院时间2。9±0。6 d。术后随访到108 例,LCC后妊娠分娩77 例,术前共分娩205 次,术后共分娩81 次;术后成功分娩(孕周>28 周)78 次(96。3%),平均分娩孕周37。4±1。7周;早产率16。7%,足月产率83。3%。孕前LCC后孕周≥28 周分娩率明显高于孕前LCC的既往分娩率(96。3%vs。10。7%,P<0。05),分娩孕周显著延长(36。4±5。5 周 vs。19。8±7。5 周,P<0。05)。不同手术指征行孕前LCC的术后分娩孕周,除手术指征为不适合TCC外(P>0。05),其余均显著晚于孕前LCC既往分娩孕周(P<0。05)。结论:孕前LCC手术安全性高,可显著延长子宫颈机能不全患者的分娩孕周改善妊娠结局,可作为既往存在TCC失败史患者的有效治疗方法。
Clinical Efficacy Analysis of Preconceptional Laparoscopic Cervical Cerclage in the Treatment of Cervical Incompetence
Objective:To evaluate the application value of preconceptional laparoscopic cervical cerclage(LCC)in improving the pregnancy outcomes with cervical incompetence(CIC).Methods:Clinical data of 112 pa-tients with CIC who underwent preconceptional LCC in The First Affiliated Hospital of Zhengzhou University from July 1,2014 to May 31,2023 were retrospectively reviewed.The surgical indications of preconceptional LCC in-cluded:failed transvaginal cervical cerclage(TCC)(42 patients),history of cervical surgery+failed TCC(7 pa-tients),unsuitability for TCC(10 patients)and strong request from patients(53 patients).The surgical situation and pregnancy outcome of preconceptional LCC were analyzed,and the gestational age of delivery before and af-ter preconceptional LCC surgery and different surgical indications were compared in postoperative delivery pa-tients who underwent preconceptional LCC.Results:The median operation time of 112 patients was 65.5 min,the median intraoperative blood loss was 10.0 ml,and there were no intraoperative complications.The postopera-tive hospital stay was 2.9±0.6 d.108 cases were followed up after surgery,with 77 cases of pregnancy and de-livery after LCC.A total of 205 deliveries were made before surgery,and 81 deliveries were made after surgery.Successful postoperative deliveries(delivery after 28 weeks)were 78(96.3% ),with an average gestational age 37.4±1.7 weeks.The preterm birth rate was 16.7%,term birth rate was 83.3% .The delivery rate at≥28 weeks after preconceptional LCC was significantly higher than the previous delivery rate of pre pregnancy LCC(96.3% vs.10.7%,P<0.05),and the gestational age was significantly prolonged(36.4±5.5 weeks vs.19.8±7.5 weeks,P<0.05).The postoperative delivery gestational week of preconceptional LCC with different surgical indi-cations was significantly later than the previous delivery gestational week of pre pregnancy LCC(P<0.05),ex-cept for the indication of unsuitability for TCC(P>0.05).Conclusions:Preconceptional LCC surgery is highly safe and can effectively prolong the gestational age and improve pregnancy outcomes in patients with CIC.It can be an effective treatment method for patients with a history of TCC failure.

Cervical incompetenceCervical cerclageLaparoscopyPreterm birthSurgical indication

刘亚娜、金玉茜、毛萌、王倩、刘雪琰、李思雨、张颖、常蕾、郭瑞霞

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郑州大学第一附属医院妇科,河南 郑州 450052

子宫颈机能不全 子宫颈环扎术 腹腔镜 早产 手术指征

河南省中青年卫生健康科技创新领军人才培养项目

YXKC2020012

2024

实用妇产科杂志
四川省医学会

实用妇产科杂志

CSTPCD北大核心
影响因子:2.564
ISSN:1003-6946
年,卷(期):2024.40(7)