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剖宫产术后再次妊娠阴道试产分娩成功的因素及母儿结局分析

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目的:探讨剖宫产术后再次妊娠阴道试产(TOLAC)成功的因素及分析母儿结局.方法:选取2019年1月至2023年6月在成都市妇女儿童中心医院产科进行TOLAC的308例孕妇作为研究组,并配对选取同时期308例瘢痕子宫直接剖宫产的孕妇作为对照组,将研究组根据分娩成功结果分为阴道分娩成功组(VBAC组)和试产失败转剖宫产组(RCD组)2个亚组.记录孕妇入院时一般情况、母儿结局等临床资料,并进行影响剖宫产术后再次经阴道分娩(VBAC)成功的单因素及多因素分析.结果:①研究期间,本院瘢痕子宫再次妊娠共计10243例,TOLAC率为3.01%,VBAC成功254例,成功率为82.46%,中转手术的前三位因素为可疑胎儿窘迫、疼痛不愿意试产、可疑子宫破裂或者先兆子宫破裂.②研究组孕妇24 h出血量、新生儿出生体质量、住院天数、住院费用均低于对照组(P<0.05).研究组亚组中,VBAC组孕妇24 h出血量、新生儿出生体质量、并发症发生率、住院天数、住院费用均低于RCD组(P<0.05).③研究组新生儿窒息率、输血率及并发症发生率与对照组比较,差异无统计学意义(P>0.05).④影响VBAC成功的单因素分析显示,VBAC组孕妇身高、Bishop评分大于RCD组,VBAC组孕妇入院时已破膜、有24周以上分娩或引产史、自然临产大于RCD组,VBAC组孕妇的宫高及胎儿估重小于RCD组(P<0.05).VBAC组与RCD组中缩宫素引产与球囊+缩宫素引产两种方式差异无统计学意义(P>0.05).⑤影响VBAC成功的多因素Logis-tic 回归分析显示,孕妇的身高≥160 cm(OR 2.461,95%CI 1.343~6.402)、Bishop评分≥6分(OR 3.420,95%CI 1.224~9.560)、入院时已破膜(OR 10.557,95%CI 1.295~86.075)、自然临产(OR 7.083,95%CI 2.659~18.868)是影响VBAC成功的独立有利因素(P<0.05).结论:VBAC具有良好的社会经济效益,对于有意愿TOLAC的孕妇入院时需结合孕妇的身高、Bishop评分、宫高、胎儿大小等来综合评估,以提高分娩成功概率,同时产时加强监护,尽早决策,以减少不良结局发生,保证母婴安全.
Analysis of Factors and Maternal and Fetal Outcomes for Successful Trial of Labor after Cesarean Section
Objective:To explore the factors of trial of labor after cesarean(TOLAC)and analyze the outcomes of mother and fetus.Methods:A total of 308 pregnant women who underwent TOLAC in the Department of Ob-stetrics of Chengdu Women and Children Center Hospital from January 2019 to June 2023 were selected as the study group,and 308 pregnant women who underwent direct cesarean section with scarred uterus during the same period were selected as the control group.The study group was divided into two subgroups according to the successful results:vaginal delivery success group(VBAC group)and trial delivery failure to cesarean section group(RCD group).Clinical data such as the general conditions of pregnant women at admission and the out-comes of mother and fetus were recorded,and the univariate and multivariate analysis was performed to analyze the factors influencing success of VBAC.Results:①A total of 10243 pregnant women were pregnant again after cesarean section,with a TOLAC rate of 3.01%and 254 cases in the VBAC group,with a success rate of 82.46%.The top three factors for conversion surgery were suspected fetal distress,pain and unwillingness to try labor,sus-pected uterine rupture or threatened uterine rupture.②The 24-hour blood loss,newborn body mass,hospitaliza-tion days and hospitalization cost of the study group were lower than those of the control group(P<0.05).In the study group,the 24-hour blood loss,newborn body mass,complication rate,hospitalization days and hospitaliza-tion cost in VBAC group were all lower than those in RCD group(P<0.05).③There was no statistically signifi-cant difference in the incidence of neonatal asphyxia,blood transfusion and complications between the study group and the control group(P>0.05).④The univariate analysis of factors affecting the success of VBAC showed that the height and Bishop score of pregnant women in VBAC group were higher than those in RCD group.Pregnant women in VBAC group had ruptured membranes at admission,had a history of delivery or in-duced labor for more than 24 weeks,and hadnatural labor was higher than those in RCD group.The uterine height and estimated fetal weight of pregnant women in VBAC group were lower than those in RCD group(P<0.05).There was no statistically significant difference between the VBAC group and the RCD group in induction of labor by oxytocin and balloon plus oxytocin(P>0.05).⑤Multivariate Logistic regression analysis showed that the height of pregnant women ≥ 160 cm(OR 2.461,95%CI 1.343-6.402)and Bishop score ≥6(OR 3.420,95%CI 1.224-9.560),membranous rupture on admission(OR 10.557,95%CI 1.295-86.075),and natural labor(OR 7.083,95%CI 2.659-18.868)were independent favorable factors for the success of VBAC(P<0.05).Conclu-sions:Vaginal delivery after cesarean section has good social and economic benefits.For pregnant women who are willing to undergo TOLAC,a comprehensive assessment should be made based on the height,Bishop score,uterine height,fetal size,etc,when admitted to the hospital to improve the probability of successful delivery.At the same time,monitoring should be strengthened during delivery and early decision should be made to reduce adverse outcomes and ensure the safety of mother and fetus.

After cesarean sectionVaginal deliveryPregnancy outcome

袁馨、唐冬梅、郑佳欣、罗丹

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成都市妇女儿童中心医院产科,四川成都 610073

剖宫产术后 阴道分娩 妊娠结局

2024

实用妇产科杂志
四川省医学会

实用妇产科杂志

CSTPCD北大核心
影响因子:2.564
ISSN:1003-6946
年,卷(期):2024.40(12)