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新疆阿拉尔地区宫颈癌筛查中HPV结果的分析

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目的 分析新疆阿拉尔地区宫颈癌筛查中的人乳头瘤病毒(HPV)检测结果。方法 选取9791例宫颈癌筛查的健康女性为研究对象,均开展HPV16、18、31、33、35、39、45、51、52、56、58、59、68型13个高危基因型检测,观察其检测结果。结果 9791例受检者中HPV总阳性检出率10。69%,其中汉族检出率与维吾尔族比较,差异无统计学意义(P>0。05);>50岁阳性检出率明显高于其他年龄段(P<0。05);单一感染阳性检出率明显高于多重感染(P<0。05);单一感染HPV分型检出率最高为52,其次是16、58及66等。HPV 52型好发于>50岁年龄段;HPV 39、31、51型好发于31~40岁年龄段,HPV 45、35型好发于21~30岁年龄段,HPV 56型好发于41~50岁年龄段。结论 新疆阿拉尔地区HPV感染率处于全国中等水平,无明显民族差异,依据该地区的HPV型分布情况,应增加疫苗接种率,促进HPV感染防控。
Analysis of HPV results in cervical cancer screening in the Alar region of Xinjiang
Objective To analyze the results of human papillomavirus(HPV)testing in cervical cancer screening in the Alar region of Xinjiang.Methods 9791 healthy women who underwent cervical cancer screening were selected as the research subjects,and 13 high-risk genotypes of HPV16,18,31,33,35,39,45,51,52,56,58,59,and 68 were tested.The test results were observed.Results Among the 9791 tested individuals,the total positive detection rate of HPV was 10.69%.Among them,there was no statistically significant difference in the detection rate between the Han ethnic group and the Uyghur ethnic group(P>0.05)The positive detection rate at the age of 50 was significantly higher than other age groups(P<0.05);The positive detection rate of single infection was significantly higher than that of multiple infections(P<0.05);The highest detection rate of HPV subtypes for single infection is 52,followed by 16,58,and 66.HPV type 52 is more common in the age group>50 years old;HPV types 39,31,and 51 are more common in the age range of 31 to 40 years old,HPV types 45 and 35 are more common in the age range of 21 to 30 years old,and HPV type 56 is more common in the age range of 41 to 50 years old.Conclusion The HPV infection rate in the Alar region of Xinjiang is at a moderate level nationwide,with no significant ethnic differences.Based on the distribution of HPV types in the region,the vaccination rate should be increased to promote HPV infection prevention and control.

XinjiangAlar regionCervical cancerHPV detection

谭玉梅、赵锋

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浙江大学医学院附属邵逸夫医院新疆兵团阿拉尔医院 检验科,新疆 阿拉尔 843300

新疆 阿拉尔地区 宫颈癌 HPV检测

2024

实用妇科内分泌电子杂志

实用妇科内分泌电子杂志

ISSN:
年,卷(期):2024.11(1)
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