首页|妇科恶性肿瘤患者宫颈部位感染病原菌分布及耐药性分析

妇科恶性肿瘤患者宫颈部位感染病原菌分布及耐药性分析

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目的 探讨妇科恶性肿瘤患者宫颈部位感染的病原菌分布与耐药性情况,为临床用药和宫颈感染防治工作提供参考。方法 回顾性分析124例妇科恶性肿瘤患者的临床资料。分析其宫颈感染情况,并对临床分离株进行收集,分析患者的宫颈部位感染病原菌分布及其耐药性。结果 在124例妇科恶性肿瘤患者中,共检出33例宫颈部位感染,宫颈感染率为26。61%。妇科恶性肿瘤宫颈感染患者在革兰阳性球菌中,主要为粪肠球菌,其对红霉素的耐药率最高,其他主要为四环素、环丙沙星、左氧氟沙星和高浓度庆大霉素。在革兰阴性杆菌中,以大肠埃希菌耐药率最高,其次为肺炎克雷伯菌和铜绿假单胞菌。结论 妇科恶性肿瘤患者宫颈部位不仅感染率较高,还具有严重的耐药性。因此,在预防和抗感染治疗时,还要充分考虑多种微生物感染特性及其耐药性,并对多重耐药菌进行强化管理。
Analysis of pathogenic bacteria distribution and drug resistance of cervical site infection in gynecological malignant tumor patients
Objective To investigate the pathogenic bacteria distribution and drug resistance of cervical site infection in gynecological malignant tumor patients,and to provide reference for clinical drug use and cervical infection prevention.Methods The clinical data of 124 patients with gynecological malignant tumor were analyzed retrospectively.The cervical infection situation was analyzed,and clinical isolates were collected to analyze the distribution and drug resistance of pathogenic bacteria in cervical site infection.Results In 124 cases of gynecological malignant tumor,33 cases of cervical site infection were detected,and the cervical infection rate was 26.61%.Among the gram-positive cocci in patients with cervical infection of gynecological malignant tumors,the main one was Enterococcus faecalis,which had the highest resistance rate to erythromycin,and the other main ones were tetracycline,ciprofloxacin,levofloxacin and high concentration gentamicin.Among gram-negative bacteria,Escherichia coli had the highest drug resistance rate,followed by Klebsiella pneumoniae and Pseudomonas aeruginosa.Conclusion Patients with gynecological malignant tumors not only have a high infection rate in the cervical area,but also have severe drug resistance.Therefore,when preventing and treating infections,it is necessary to fully consider the characteristics of multiple microbial infections and their resistance,and strengthen the management of multidrug-resistant bacteria.

Gynecological malignancyCervical site infectionDrug resistance

刘阳

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忻州职业技术学院 基础医学教研室,山西 忻州 034000

妇科恶性肿瘤 宫颈部位感染 耐药性

2024

实用妇科内分泌电子杂志

实用妇科内分泌电子杂志

ISSN:
年,卷(期):2024.11(1)
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