实用妇科内分泌电子杂志2024,Vol.11Issue(1) :76-78.DOI:10.3969/j.issn.2095-8803.2024.01.024

右美托咪定不同给药方式在腹腔镜子宫肌瘤术中的麻醉效果比较

Comparison of anesthetic effect of dexmedetomidine with different administration modes in laparoscopic hysteromyoma

张宇华
实用妇科内分泌电子杂志2024,Vol.11Issue(1) :76-78.DOI:10.3969/j.issn.2095-8803.2024.01.024

右美托咪定不同给药方式在腹腔镜子宫肌瘤术中的麻醉效果比较

Comparison of anesthetic effect of dexmedetomidine with different administration modes in laparoscopic hysteromyoma

张宇华1
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作者信息

  • 1. 江苏省海门市中医院 麻醉科,江苏 海门 226100
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摘要

目的 观察右美托咪定不同给药方式在腹腔镜子宫肌瘤术中的麻醉效果,探讨合适给药方式.方法 选取286例行腹腔镜手术治疗的子宫肌瘤患者,按照入院日期分为研究组(单号)与参照组(双号),每组143例.两组均接受全身麻醉,参照组持续静脉泵注0.3μg/(kg·h)右美托咪定,至手术完毕前20 min;研究组单次静脉注射0.6μg/kg右美托咪定,15 min内缓慢完成注射.比较两组麻醉效果.结果 研究组手术时间及麻醉恢复时间短于参照组(P<0.05).研究组患者建立气腹后5 min(T1)、建立气腹后30 min(T2)的心率(HR)及平均动脉压(MAP)水平高于参照组(P<0.05).研究组不良反应发生率7.69%低于参照组的18.18%(P<0.05).结论 单次注射右美托咪定给药方式用于子宫肌瘤行腹腔镜手术患者中,可稳定血流动力学指标,缩短手术、恢复、拔管及苏醒时间,减少不良反应发生,值得临床应用.

Abstract

Objective To observe the anesthetic effect of different administration methods of dexmedetomidine in laparoscopic hysteromyoma surgery and explore the appropriate administration methods.Methods 286 patients with uterine fibroids undergoing laparoscopic surgery were selected and divided into study group(single number)and reference group(double number)according to the admission date,with 143 cases in each group.Both groups received general anesthesia,and the reference group was injected with 0.3 μg/(kg·h)dexmedetomidine intravenously until 20 minutes before the operation.The study group received a single intravenous injection of 0.6 μg/kg dexmedetomidine,which was completed slowly within 15 minutes.The anesthetic effect of the two groups was compared.Results The operation time and anesthesia recovery time of the study group were shorter than those of the control group(P<0.05).The heart rate(HR)and mean arterial pressure(MAP)levels of 5 min(T1)and 30 min(T,)after pneumoperitoneum establishment in the study group were higher than those in the reference group(P<0.05).The incidence of adverse reactions in the study group was 7.69%lower than that in the reference group(18.18%)(P<0.05).Conclusion Single injection of dexmedetomidine can stabilize hemodynamics,shorten the time of operation,recovery,extubation and recovery,and reduce the occurrence of adverse reactions in patients with uterine fibroids undergoing laparoscopic surgery,which is worthy of clinical application.

关键词

腹腔镜/子宫肌瘤术/右美托咪定/麻醉方式

Key words

Laparoscopy/Hysteromyoma/Dexmedetomidine/Mode of anesthesia

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出版年

2024
实用妇科内分泌电子杂志

实用妇科内分泌电子杂志

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