Observation on the effect of folic acid supplementation during pregnancy on preventing neural tube defects in fetus
Objective To explore the clinical value of folic acid supplementation during pregnancy to prevent neural tube defects in fetus.Methods From January to December 2021,5768 women in the first 3 months of pregnancy and pregnant women in the first trimester were selected as the control group;In addition,5422 women in the first 3 months of pregnancy and pregnant women in the first trimester were selected as the observation group from January to December 2022.In the control group,pregnant women were instructed to eat reasonably according to their examination conditions during pregnancy preparation and delivery,and were instructed to routinely supplement folic acid(400μg/d)until 3 months after pregnancy.The observation group received health care management based on the control group.Medication compliance,folic acid knowledge score and incidence of neural tube defects were compared between the two groups.Results The good compliance rate of the observation group was 94.61％,the folic acid knowledge score(90.70±3.44)was higher than that of the control group(84.78％)and that of the control group(85.34±6.23),respectively.The incidence of neural tube defects in the observation group was 0.09％lower than that of the control group(0.26％)(P＜0.05).Conclusion Strengthening folic acid supplementation management during pregnancy can improve pregnant women's folic acid medication compliance and knowledge of folic acid,reduce the incidence of neural tube defects,and is worthy of clinical application.
万方数据
维普
