Clinical efficacy of low-molecular-weight heparin sodium combined with low-dose progesterone in the treatment of threatened miscarriage and its impact on pregnancy outcomes
Objective To exploring the clinical efficacy of low-molecular-weight heparin sodium combined with low-dose progesterone in the treatment of threatened miscarriage and its impact on pregnancy outcomes.Methods 90 pregnant women with threatened miscarriage were selected and divided into a study group(50 cases)and a control group(40 cases)based on different treatment methods.The control group received low-dose progesterone treatment,while the study group received a combination of low-molecular-weight heparin sodium treatment on the basis of the control group.Compare the clinical efficacy,levels of pre thrombotic state markers,and pregnancy outcomes between two groups.Results The total effective rate of the study group(94.00％)was higher than that of the control group(80.00％)(P＜0.05).The full-term pregnancy rate of the study group was higher than that of the control group,and the abortion rate was lower than that of the control group(P＜0.05).There was no significant difference in the preterm birth rate between the two groups(P＞0.05).After treatment,the level of plasminogen(PLG)in the study group was higher than that in the control group,and the level of protein C(PC)was lower than that in the control group(P＜0.05).Conclusion The combination of low-molecular-weight heparin sodium and low-dose progesterone in the treatment of threatened miscarriage women can regulate the levels of pre thrombotic state markers,improve clinical efficacy,and improve pregnancy outcomes,which is worthy of clinical promotion.
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