Efficacy and safety evaluation of carboprost tromethamine in preventing postpartum hemorrhage in high-risk cesarean section women
Objective To investigate the application value and safety of carboprost tromethamine in high-risk cesarean section.Methods 128 high-risk cesarean section parturients were selected and randomly divided into a control group and a study group,with 64 cases in each group,using a random number table method.After cesarean section in the lower segment of the uterus,the fetus was delivered.The control group received intervention with oxytocin,while the study group received intervention with carboprost tromethamine.Compare the bleeding volume,postpartum bleeding rate,red blood cell count,hemoglobin level,and incidence of adverse reactions between two groups of parturients at different stages.Results The study group had less bleeding at 2 and 24 hours after cesarean section compared to the control group,and the postpartum bleeding rate was 1.56％lower than the control group's 10.94％(P＜0.05).After 2 hours of surgery,the red blood cell count and hemoglobin level in the study group were higher than those in the control group(P＜0.05).There was no statistically significant difference in the incidence of adverse reactions between the two groups(P＞0.05).Conclusion The application of carboprost tromethamine in high-risk cesarean section can effectively prevent postpartum hemorrhage,and it is safe and worthy of clinical application.
万方数据
维普
