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宫颈脱落细胞特殊染色技术在宫颈癌筛查中的应用效果

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目的 探讨宫颈脱落细胞特殊染色技术在宫颈癌筛查中的应用效果。方法 选取本院妇科门诊101名宫颈癌筛查女性为研究对象,均进行液基薄层细胞(TCT)和宫颈脱落细胞特殊染色技术检查,以阴道镜下宫颈活检病理结果为金标准,比较两种检查方法的诊断效能。结果 宫颈组织病理学检查显示阳性35例,阳性率为34。7%;TCT检查的敏感度为31。7%、特异度为61。0%、阳性预测值为54。3%、阴性预测值为37。9%、准确度为43。6%,低于宫颈脱落细胞特殊染色技术的46。5%、74。1%、57。1%、65。2%、62。3%。结论 宫颈脱落细胞特殊染色技术为无损伤检查,具有便携性高、操作简单、检测快速、经济实用和不依赖病理医师等特点,适用于人群普查或检测技术设备相对落后的偏远地区宫颈癌普查,也适合基层医院宫颈癌普查。
The application effect of special staining technology for cervical exfoliated cells in cervical cancer screening
Objective To exploring the application effect of special staining techniques for cervical exfoliated cells in cervical cancer screening.Methods 101 women screened for cervical cancer in the gynecological outpatient department of our hospital were selected as the research subjects,all of whom underwent liquid based thin-layer cell(TCT)and special staining techniques for cervical exfoliated cells.The pathological results of cervical biopsy under colposcopy were used as the gold standard to compare the diagnostic efficacy of the two examination methods.Results The pathological examination of cervical tissue showed 35 positive cases,with a positive rate of 34.7%;The sensitivity of TCT examination was 31.7%,specificity was 61.0%,positive predictive value was 54.3%,negative predictive value was 37.9%,and accuracy was 43.6%,which was lower than the 46.5%,74.1%,57.1%,65.2%,and 62.3%of cervical exfoliated cell special staining techniques.Conclusion The special staining technique for cervical exfoliated cells is a non-invasive examination,with high portability,simple operation,fast detection,economic practicality,and no dependence on pathologists.It is suitable for population census or cervical cancer census in remote areas with relatively backward detection technology and equipment,as well as for cervical cancer census in grassroots hospitals.

Cervical cancerScreeningDiagnosisSpecial staining technique for cervical exfoliated cellsCervical tissue pathology

黄府清、蒋群、蔡辉英、周恒、丁微、张流、阳晓敏

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柳州市妇幼保健院妇科门诊,广西柳州 545001

宫颈癌 筛查 诊断 宫颈脱落细胞特殊染色技术 宫颈组织病理学

2024

实用妇科内分泌电子杂志

实用妇科内分泌电子杂志

ISSN:
年,卷(期):2024.11(2)
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