首页|多西他赛静脉化疗联合动脉介入栓塞治疗中晚期宫颈癌效果评价

多西他赛静脉化疗联合动脉介入栓塞治疗中晚期宫颈癌效果评价

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目的 探讨多西他赛静脉化疗联合动脉介入栓塞治疗中晚期宫颈癌的临床效果。方法 选取本院收治的108例中晚期宫颈癌患者为研究对象,按照随机数字表法分为两组,各54例。静脉化疗组应用多西他赛联合卡铂化疗方案,联合治疗组在静脉化疗组的基础上采取双侧子宫动脉灌注化疗栓塞术治疗。观察两组近期疗效及治疗过程中的不良反应发生率。结果 联合治疗组近期疗效总有效率为96。30%,高于静脉化疗组的83。33%,差异有统计学意义(P<0。05)。联合治疗组与静脉化疗组不良反应发生率比较差异无统计学意义(P>0。05)。结论 多西他赛联合子宫动脉介入栓塞化疗治疗宫颈癌效果显著,能协同增效,提高抗肿瘤效果,且不增加毒副作用,值得在临床推广与应用。
Evaluation of the efficacy of intravenous chemotherapy with docetaxel combined with arterial embolization in the treatment of advanced cervical cancer
Objective To explore the clinical efficacy of intravenous chemotherapy with docetaxel combined with arterial embolization in the treatment of advanced cervical cancer.Methods 108 patients with advanced cervical cancer admitted to our hospital were selected as the research subjects.They were randomly divided into two groups using a random number table method,with 54 cases in each group.The intravenous chemotherapy group received a combination of docetaxel and carboplatin chemotherapy regimen,while the combined treatment group received bilateral uterine artery infusion chemotherapy embolization on the basis of the intravenous chemotherapy group.Observe the recent efficacy and incidence of adverse reactions during treatment in two groups.Results The total effective rate of the combined treatment group in the short term was 96.30%,which was higher than 83.33%in the intravenous chemotherapy group,and the difference was statistically significant(P<0.05).There was no statistically significant difference in adverse reactions between the combination therapy group and the intravenous chemotherapy group(P>0.05).Conclusion The combination of docetaxel and uterine artery embolization chemotherapy has a significant effect on the treatment of cervical cancer,which can synergistically enhance the efficacy,improve the anti-tumor effect,and do not increase toxic side effects.It is worth promoting and applying in clinical practice.

DocetaxelChemotherapyArterial intervention embolizationMiddle to late stageCervical carcinoma

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南通瑞慈医院(扬州大学第四临床医学院)肿瘤内科,南通 江苏 226000

多西他赛 化疗 动脉介入栓塞 中晚期 宫颈癌

2024

实用妇科内分泌电子杂志

实用妇科内分泌电子杂志

ISSN:
年,卷(期):2024.11(3)
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