首页|血清激素联合免疫抗体检测在不孕筛查中的应用观察

血清激素联合免疫抗体检测在不孕筛查中的应用观察

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目的 观察在不孕不育筛查中开展血清激素联合免疫抗体的实际效果。方法 选取本院120例不孕患者作为干预组,并在同期纳入120例生育功能正常人群作为参照组,均对其开展血清激素与免疫抗体检测,比较分析两组检测结果。结果 干预组血清激素水平高于参照组,差异有统计学意义(P<0。05)。月经周期失调者血清激素水平高于月经周期正常者,差异有统计学意义(P<0。05)。卵巢功能低下者血清激素水平高于卵巢功能正常者,差异有统计学意义(P<0。05)。干预组免疫抗体中抗透明带抗体(ZPAb)、抗子宫内膜抗体(EmAb)、抗心磷脂抗体(ACAb)、抗绒毛膜促性腺激素抗体(AhAb)的阳性检出率高于参照组,差异有统计学意义(P<0。05)。继发性不孕免疫抗体中ZPAb、EmAb、ACAb、AhAb的阳性检出率高于原发性不孕,差异有统计学意义(P<0。05)。结论 不孕筛查时采用血清激素与免疫抗体检测效果均确切可行,两种联合检测能够有效发挥协同效应,提升临床不孕不育检出率,为后期治疗工作的开展奠定基础,在临床中具有较高的应用价值。
Application observation of serum hormone combined with immune antibody detection in infertility screening
Objective To observe the actual effect of serum hormone combined with immune antibodies in infertility screening.Methods 120 infertile patients from our hospital were selected as the intervention group,and 120 individuals with normal reproductive function were included as the reference group during the same period.Serum hormone and immune antibody tests were conducted on them,and the test results of the two groups were compared and analyzed.Results The serum hormone levels in the intervention group were higher than those in the control group,and the difference was statistically significant(P<0.05).The serum hormone levels in patients with menstrual cycle disorders were higher than those with normal menstrual cycles,and the difference was statistically significant(P<0.05).The serum hormone levels in patients with low ovarian function were higher than those with normal ovarian function,and the difference was statistically significant(P<0.05).The positive detection rates of anti zona pellucida antibody(ZPAb),anti endometrial antibody(EmAb),anti cardiolipin antibody(ACAb),and anti chorionic gonadotropin antibody(AhAb)in the intervention group were higher than those in the control group,and the difference was statistically significant(P<0.05).The positive detection rates of ZPAb,EmAb,ACAb and AhAb in secondary infertility immune antibodies were higher than those in primary infertility,and the difference was statistically significant(P<0.05).Conclusion The use of serum hormones and immune antibodies for infertility screening is both effective and feasible.The combination of the two tests can effectively exert a synergistic effect,improve the detection rate of clinical infertility,lay the foundation for the development of later treatment work,and have high application value in clinical practice.

InfertilityImmune antibodySerum hormonePrepregnancy screening

梁媚珍、梁锦伦、李厦洁

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东莞市石碣医院妇产科,广东 东莞 523290

不孕 免疫抗体 血清激素 孕前筛查

2024

实用妇科内分泌电子杂志

实用妇科内分泌电子杂志

ISSN:
年,卷(期):2024.11(3)
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