首页|DNA倍体定量分析、HPV检测和液基细胞学在宫颈癌筛查中的应用价值

DNA倍体定量分析、HPV检测和液基细胞学在宫颈癌筛查中的应用价值

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目的 探究DNA倍体定量分析、人乳头瘤病毒(HPV)检测和液基细胞学(TCT)在筛查宫颈癌中的应用价值。方法 选取120例宫颈癌筛查患者,予DNA倍体定量分析、HPV检测、TCT检测,以病理学检测为诊断金标准,计算并分析各检测方式的诊断效能。结果 DNA倍体定量分析、HPV检测、TCT检测阳性率分别为68。33%、71。67%、72。50%,联合检测阳性率为70。83%。联合检测敏感度、诊断符合率高于DNA倍体定量分析、HPV检测、TCT检测(P<0。05)。联合检测诊断效能高于DNA倍体定量分析、HPV检测、TCT检测(P<0。05)。结论 DNA倍体定量分析、HPV检测和TCT检测均能有效筛查宫颈癌,但联合检测诊断效能更高,可实现宫颈癌早发现早治疗,降低宫颈癌发病率和病死率,值得临床推广与应用。
The application value of DNA ploidy quantitative analysis,HPV detection,and liquid based cytology in screening cervical cancer
Objective To explore the application value of DNA ploidy quantitative analysis,human papillomavirus(HPV)detection,and liquid based cytology(TCT)detection in screening for cervical cancer.Method 120 cervical cancer screening patients were selected and subjected to DNA ploidy quantitative analysis,HPV testing,and TCT testing.Using pathological testing as the diagnostic gold standard,calculate and analyze the diagnostic efficacy of each testing method.Results The positive rates of DNA ploidy quantitative analysis,HPV detection,and TCT detection were 68.33%,71.67%,and 72.50%,respectively.The positive rate of combined detection was 70.83%.The sensitivity and diagnostic accuracy of joint detection were higher than those of DNA ploidy quantitative analysis,HPV detection,and TCT detection(P<0.05);The diagnostic efficiency of joint testing is higher than that of DNA ploidy quantitative analysis,HPV detection,and TCT detection(P<0.05).Conclusion DNA ploidy quantitative analysis,HPV detection and TCT detection can effectively screen cervical cancer,but the combined detection and diagnosis are more effective,which can realize early detection and treatment of cervical cancer,reduce the incidence rate and mortality of cervical cancer,and is worthy of clinical promotion and application.

Cervical cancerDNA ploidy quantitative analysisHPV detectionLiquid based cytology detection

王迪

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辽源市妇幼保健计划生育服务中心妇女保健科,吉林辽源 136200

宫颈癌 DNA倍体定量分析 HPV检测 液基细胞学检测

2024

实用妇科内分泌电子杂志

实用妇科内分泌电子杂志

ISSN:
年,卷(期):2024.11(3)
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