未足月胎膜早破发病机制的研究进展
Research progress on pathogenesis of premature rupture of membranes before term
赖锦文 1叶青 1蔡雨静 1梁雄1
作者信息
- 1. 暨南大学珠海临床医学院(珠海市人民医院)产科,广东 珠海 519000
- 折叠
摘要
未足月胎膜早破(PPROM)在产科中是一种出现频率较高且风险较大较难处理的产科并发症,是导致胎儿早产的主要原因之一,若不能及时给予针对性的处理,会严重威胁母儿生命.在现有研究中,PPROM与许多因素有关,如生殖道感染、母胎因素、不良生活习惯及遗传相关疾病等,之间相互作用和影响,最终导致胎膜降解和破裂.未足月胎膜早破的有着复杂的发病机制,本文通过综述PPROM发病机制的研究进展,讨论导致胎膜弱化的危险因素以及机制,为降低PPROM发生率提供线索和方法.
Abstract
Preterm rupture of membranes(PPROM)is a kind of obstetric complication with high frequency and greater risk in obstetrics,which is one of the main reasons leading to premature delivery of fetus.If not timely targeted treatment,it will seriously threaten the life of mother and child.In the existing studies,PPROM is related to many factors,such as reproductive tract infection,maternal-fetal factors,bad living habits,genetic related diseases,etc.,and their interaction and influence ultimately lead to the degradation and rupture of fetal membrane.Preterm premature rupture of fetal membrane has a complex pathogenesis.This article reviews the research progress in the pathogenesis of PPROM,discusses the risk factors and mechanisms leading to weakening of fetal membrane,and provides clues and methods for reducing the incidence of PPROM.
关键词
综述/未足月胎膜早破/研究进展/发病机制Key words
Review/Premature rupture of membranes before term/Research progress/Pathogenesis引用本文复制引用
出版年
2024
NETL
NSTL
万方数据